Career Awards for Medical Scientists

Grant Recipients

2014
2013
2012
2011
2009
2008
2007

2014

Theresa Alenghat, D.V.M., Ph.D.
University of Pennsylvania
Epigenomic regulation of the host-commensal relationship

Christina Eleanor Barkauskas, M.D.
Duke University
Epithelial-mesenchymal crosstalk in lung fibrosis and alveolar homeostasis

James Edward Cassat, M.D., Ph.D.
Vanderbilt University School of Medicine
Contribution of host and pathogen to altered bone homeostasis and bacterial survival during osteomyelitis

Kevin Jon Cheung, M.D.
Johns Hopkins University
Elucidating the Role of K14+ Leader Cells in Breast Cancer Invasion and Metastasis

Ethan Michael Goldberg, M.D., Ph.D.
University of Pennsylvania Perelman School of Medicine
Analysis of circuit function informs novel therapeutic interventions in an epilepsy model

Malay Haldar, M.D., Ph.D.
Washington University School of Medicine
Transcription factor SPI-C at the interface of iron homeostasis and innate immunity.

Marcin Imielinski, M.D., Ph.D.
Harvard Medical School
Reconstructing complex loci in lung adenocarcinoma with large-insert whole genome sequencing

Jeffery M Klco, M.D., Ph.D.
Washington University School of Medicine
Role of Notch Signaling in the Bone Marrow Stroma

Jason Knight, M.D., Ph.D.
University of Michigan-Ann Arbor
Innate immunity in the pathogenesis of lupus and antiphospholipid vasculopathy

Anita Katherine McElroy, M.D., Ph.D.
Emory University School of Medicine
Defining the roles of CD4+ T cells in generating a protective immune response against Rift Valley fever virus

Sudarshan Rajagopal, M.D., Ph.D.
Duke University Medical Center
Dissecting Receptor Signaling Pathways in Pulmonary Hypertension

Sean Robinson Stowell, M.D., Ph.D.
Emory University School of Medicine
Elucidating Mechanisms of Innate Immunity Against Molecular Mimicry

2013

Susanne Elizabeth Ahmari, M.D., Ph.D.
Columbia University
Testing the Role of Cortico-Striatal Circuits in Obsessive Compulsive Disorder Pathology and Treatment

Gautam Bhave, M.D., Ph.D.
Vanderbilt University Medical Center
Role of Peroxidasin and Protein Halogenation in Diabetic Nephropathy

Ajai Arvind Dandekar, M.D., Ph.D.
University of Washington
Quorum sensing and mechanisms to ensure cooperation in the opportunistic pathogen Pseudomonas aeruginosa

Andrew Eugene Hermann Elia, M.D., Ph.D.
Harvard Medical School
Proteomic analysis of ubiquitination and protein stability in the DNA damage response

Gaorav P Gupta, M.D., Ph.D.
Memorial Sloan-Kettering Cancer Center
DNA Damage Responses in Breast Cancer Pathogenesis

Andrew Caleb Hsieh, M.D.
University of California-San Francisco
Elucidating the role of aberrant translational control on prostate cancer invasion and metastasis

Jean-Sebastien Joyal, M.D., Ph.D.
University of Montreal Faculty of Medicine
Neuronal Energy Metabolism Drives Angiogenesis

Alex Kentsis, M.D., Ph.D.
Harvard Medical School
Tumorigenesis by endogenous DNA transposons in human cancer.

Jeniel Emily Nett, M.D., Ph.D.
University of Wisconsin-Madison
Mechanisms of Candida Biofilm Immune Evasion

Rhea Myers Sumpter, Jr., M.D., Ph.D.
University of Texas Southwestern Medical Center-Dallas
A novel role for FANCC in selective autophagy 

2012

Chetan Bettegowda, M.D., Ph.D.
Johns Hopkins University
Translational molecular profiling of oligodendrogliomas

Scott Richard Floyd, M.D., Ph.D.
Massachusetts Institute of Technology
Insulating chromatin from DNA damage signaling: epigenetic modifications and connections to human cancer

Benjamin Elison Gewurz, M.D., Ph.D.
Harvard Medical School
Identification of novel NFkB pathway components important for lymphomagenesis

Michael Rosenblum, M.D., Ph.D.
University of California-San Francisco
Memory regulatory T cells in inflammatory and autoimmune disease

Michael Thomas Spiotto, M.D., Ph.D.
University of Chicago
Identification of chromosomal aberrations that cooperate with the human papillomavirus to cause cancer

David Tsai Ting, M.D.
Harvard Medical School
Characterization of non-coding RNAs in pancreatic adenocarcinoma

Richard Chih-Chien Wang, M.D., Ph.D.
University of Texas Southwestern Medical Center-Dallas
Akt-mediated regulation of autophagy & tumorigenesis through formation of a beclin 1/keratin intermediate filament complex

Kelley Yan, M.D., Ph.D.
Stanford University
Regulation of active and quiescent intestinal stem cells

Ellen Yeh, M.D., Ph.D.
Stanford University
Function of the plastid organelle in P. falciparum: beyond isoprenoid precursor biosynthesis and blood stage

Hao Zhu, M.D.
Harvard University
Investigating the Lin28/let-7 pathway in mouse models of liver cancer and regeneration

2011

Karin Elisabeth Finberg, M.D., Ph.D.
Duke University School of Medicine
Identification of Novel Genetic Regulators of Mammalian Iron Homeostasis

Karunesh Ganguly, M.D., Ph.D.
University of California-San Francisco
Control of a Complex Neuroprosthetic Device using Electrocorticography

Douglas Sun Kwon, M.D., Ph.D.
Harvard Medical School
New technologies for the study of HIV mucosal immunity and compartmentalization in the female genital tract

Nikhil Vilas Munshi, M.D., Ph.D.
University of Texas Southwestern Medical Center-Dallas
Genomic Approaches to Understanding the Cis-Regulatory Architecture of the Atrioventricular Node

Stacey Lynn Rentschler, M.D., Ph.D.
University of Pennsylvania
Role of notch signaling in preexcitation and arrhythmias

Joshua Marc Shulman, M.D., Ph.D.
Harvard Medical School
Exploring the Genetics of Parkinson's Disease in Humans and Drosophila

Eric Lee Snyder, M.D., Ph.D.
Massachusetts Institute of Technology
Regulation of lung cancer progression by the cell fate determinant Nkx2.1

Christopher Ryan Vakoc, M.D., Ph.D.
Cold Spring Harbor Laboratory
Identifying epigenetic vulnerabilities in chemotherapy-resistant leukemia

Kevin Chun-Kai Wang, M.D., Ph.D.
Stanford University
Mechanisms of transcriptional regulation by long noncoding RNAs in partnership with chromatin modifying complexes

Duane Robert Wesemann, M.D., Ph.D.
Harvard Medical School
Extramedullary B Cell Development in the Gut Lamina Propria

 

2009

Chester Drum, M.D., Ph.D.
Massachusetts Institute of Technology
Protein nanoparticles for small molecule drug delivery

Pradipta Ghosh, M.D.
University of California-San Diego
Modulation of G-protein activity during oncogenic and metastatic progression

Matthew Vander Heiden, M.D., Ph.D.
Harvard Medical School
Metabolic control of cancer cell proliferation by pyruvate kinase M2

Quyen T. Nguyen, M.D., Ph.D.
University of California-San Diego
Testing surgery guided by molecular fluorescence imaging

Ann Zovein, M.D.
University of California-Los Angeles
Hemogenic endothelium: hematopoietic stem cell emergence from the vasculature

2008

Antonios O. Aliprantis, M.D., Ph.D.
Harvard School of Public Health
Novel regulators of the osteoclast differentiation program

Kathleen H. Burns, M.D., Ph.D.
Johns Hopkins University
Role of retrotransposons in hematopoietic neoplasias

Daniel Cahill, M.D., Ph.D.
Harvard School of Public Health
Translational molecular genetic analyses of chemotherapeutic resistance in human brain tumors

Alice Siau-In Chen-Plotkin, M.D.
University of Pennsylvania
Genomic approaches to frontotemporal dementia

Sandeep Robert Datta, M.D., Ph.D.
Columbia University
Characterization of neural circuits that drive innate behaviors

Joseph Alexander Duncan, M.D., Ph.D.
University of North Carolina-Chapel Hill
Dissecting cryopyrin-mediated inflammatory signaling and its role in the pathogenesis of infectious diseases

Wendy Sarah Garrett, M.D., Ph.D.
Harvard School of Public Health
Novel effectors and regulators of inflammation, chronic infection, and carcinogenesis in the colon

Jeffrey Parker Henderson, M.D., Ph.D.
Washington University
Iron acquisition by bacterial siderophores as a pathogenic determinant in urinary track infections

Lu Quang Le, M.D., Ph.D.
University of Texas Southwestern Medical Center-Dallas
Cell of origin and tumor microenvironment in NF1-associated neurofibroma development

Ravindra Majeti, M.D., Ph.D.
Stanford University
Identification and targeting of human acute myeloid leukemia stem cell-specific cell surface molecules

Heather Christy Mefford, M.D., Ph.D.
University of Washington
Novel genomic rearrangements in developmental pediatric disorders

Ken Nakamura, M.D., Ph.D.
University of California-San Francisco
Physiologic and pathologic interactions of alpha-synuclein with mitochondria in Parkinson's disease

Robert M. Plenge, M.D., Ph.D.
Harvard Medical School
Genotype-phenotype studies of rheumatoid arthritis susceptibility genes

David Tevis Pride, M.D., Ph.D.
Stanford University
Bacteriophage communities in oral health and disease

Miguel Nicolas Rivera, M.D.
Harvard Medical School
Characterization of a novel X-linked tumor suppressor, WTX, in pediatric cancer

Agata Smogorzewska, M.D., Ph.D.
Harvard Medical School
Role of the Fanconi Anemia and other DNA crosslink repair pathways in genome maintenance and cancer prevention

 

2007

Jonathan Paul Alexander, M.D., Ph.D.
University of California-San Francisco
Isolation of a putative alveolar stem cell population and analysis of its role in development, maintenance, and repair of the lung epithelium

Robert Baloh, M.D., Ph.D.
Washington University
Mechanism of peripheral neuropathy from Mitofusin 2 mutations

James Elliott Bradner, M.D.
Harvard University
Design and characterization of highly potent inhibitors of HDAC6

Clark C. Chen, M.D., Ph.D.
Harvard Medical School
The molecular basis and therapeutic implications of genome instability during brain tumor progression

Arlene Dent, M.D., Ph.D.
Case Western Reserve University
Acquisition of immunity to blood stage Falciparum malaria in infants

Mahalia Sabrina Desruisseaux, M.D.
Albert Einstein College of Medicine of Yeshiva University
Neuroparasitology: neurological complications of cerebral malaria

Jay F. Dorsey, M.D., Ph.D.
University of Pennsylvania
Identification of mSin3b and Mad4 as novel p53 target genes directing p53-mediated transcriptional repression

Benjamin Levine Ebert, M.D., Ph.D.
Harvard Medical School
Genomic approaches to disorders of erythroid differentiation

Brian Todd Edelson, M.D., Ph.D.
Washington University
Macrophage and dendritic cell development

Rene L. Galindo, M.D., Ph.D.
University of Texas Southwestern Medical Center-Dallas
Genetic dissection of the Rhabdomyosarcoma initiator PAX-FKHR and PAX-related signaling in skeletal muscle development

Darnell Kaigler, D.D.S., Ph.D.
University of Michigan-Ann Arbor
Cell therapy for the treatment of alveolar bone defects

Michael Z. Lin, M.D., Ph.D.
University of California-San Diego
Elucidating mechanisms of synaptic plasticity and learning by visualizing and controlling local protein turnover

Roger Lo, M.D., Ph.D.
University of California-Los Angeles
Melanoma in the skin: initiation, progression, and crosstalk with dermal fibroblasts

Emanual Maverakis, M.D.
University of California-Davis
gC399tr an inhibitor of autoimmunity

Eric Matthew Morrow, M.D., Ph.D.
Harvard Medical School
Identification of autism genes in special founder populations using high-density SNP microarrays

Christopher Newton-Cheh, M.D.
Harvard Medical School
Genomic dissection of QT interval duration and sudden death

Dao Nguyen, M.D.
University of Washington
Stringent response in Pseudomonas aeruginosa biofilm formation and antibiotic tolerance

Anil Potti, M.D.
Duke University
Gene expression patterns coupled with signatures of oncogenic pathway deregulation provide a novel approach to targeted therapeutics in non-small cell lung carcinoma

Frank J. Probst, M.D., Ph.D.
Baylor College of Medicine
Generation of mouse models for X-linked diseases

Joseph C. Wu, M.D., Ph.D.
Stanford University
Molecular and cellular mechanisms of cardiac regeneration

Mark Nan Wu, M.D., Ph.D.
University of Pennsylvania
Identification of novel genes that regulate sleep in Drosophila melanogaster