Career Awards for Medical Scientists

Grant Recipients

2016
2015
2014
2013
2012

Awardees 2011-2007

2016

Jonathan Abraham, M.D., Ph.D.
Harvard Medical School
Profiling the human antibody response in survivors of viral hemorrhagic fevers

Heidi Leigh Cook-Andersen, M.D., Ph.D.
University of California-San Diego
Post-transcriptional gene regulation during the mammalian oocyte-to-embryo transition

Mariella Gruber Filbin, M.D., Ph.D.
Harvard Medical School
Discovering novel epigenetic dependencies in pediatric high-grade glioma

Andrew Michael Intlekofer, M.D., Ph.D.
Memorial Sloan-Kettering Cancer Center
Investigating L-2-hydroxyglutarate production and its relevance to normal hematopoiesis and leukemogenesis

Siddhartha Jaiswal, M.D., Ph.D.
Harvard Medical School
Elaborating the causal link between clonal hematopoiesis and atherosclerosis

Devanand Sadanand Manoli, M.D., Ph.D.
University of California-San Francisco
Genetic models of social attachment in development and mental illness

Alexander Marson, M.D., Ph.D.
University of California-San Francisco
Molecular characterization of non-coding genetic variants that promote human autoimmunity

Seth Rakoff-Nahoum, M.D., Ph.D.
Harvard Medical School
Gut microbiota ecological interaction networks in health and disease

Dhakshin Ramanathan, M.D., Ph.D.
University of California-San Francisco
Role of spindle oscillations in modulating neural plasticity and procedural memory consolidation

Tiffany Crawford Scharschmidt, M.D.
University of California-San Francisco
Elucidating mechanisms of immune tolerance to skin commensal bacteria

Alexander Spektor, M.D., Ph.D.
Harvard Medical School
The mechanism of DNA damage and chromothripsis from chromosome segregation errors

Bruce Mao Zheng Wang, M.D.
University of California-San Francisco
Wnt signaling and hepatocyte stem cells in liver homeostasis and cancer
 

2015

Jennifer M Alexander-Brett, M.D., Ph.D.
Washington University
Targeting the Regulatory Mechanism of the Nucleokine IL-33

Daniel Evan Bauer, M.D., Ph.D.
Harvard Medical School
Functional Characterization of Trait-Associated Enhancers

James Toliver Bennett, M.D., Ph.D.
University of Washington
Impact of Somatic Mutations on Birth Defects

Shadmehr Demehri, M.D., Ph.D.
Harvard Medical School
Local and Systemic Effects of TSLP on Cancer

Charles Gawad, M.D.
University  of Tennessee Health Science Center College of Medicine
Defining the Cellular and Genetic Origins of Childhood Acute Lymphoblastic Leukemia using Single-Cell Genomics

Matthew Blake Greenblatt, M.D., Ph.D.
Weill Cornell Medical College
Novel Mechanisms of Bone Formation

Rajan Jain, M.D.
University of Pennsylvania Perelman School of Medicine
Nuclear lamina-chromatin interactions are drivers of cardiac progenitor cell commitment

Matthew Stern Kayser, M.D., Ph.D.
University of Pennsylvania Perelman School of Medicine
A role for sleep in synapse development and susceptibility to neuropsychiatric disorders

Dan Avi Landau, M.D., Ph.D.
Weill Cornell Medical College
Genetic and Epigenetic Determinants of Chronic Lymphocytic Leukemia Evolution

Kory Joshua Lavine, M.D., Ph.D.
Washington University School of Medicine
Distinct Macrophage Lineages Govern Cardiac Recovery and Heart Failure Progression

Bluma J. Lesch, M.D., Ph.D.
Massachusetts Institute of Technology
Evolutionary and functional characterization of poised chromatin in the mammalian germ line

Joseph Douglas Mancias, M.D., Ph.D.
Harvard Medical School
Role of ferritinophagy in iron metabolism and pancreatic cancer

Anna Victoria Rotberg Molofsky, M.D., Ph.D.
University of California-San Francisco
Astrocyte-Encoded Regional cues in Developmental Synapse Formation

Sahar Nissim, M.D., Ph.D.
Harvard Medical School
Discovery, Validation, and Characterization of Novel Familial Pancreatic Cancer Genes

2014

Theresa Alenghat, D.V.M., Ph.D.
University of Cincinnati
Epigenomic regulation of the host-commensal relationship

Christina Eleanor Barkauskas, M.D.
Duke University
Epithelial-mesenchymal crosstalk in lung fibrosis and alveolar homeostasis

James Edward Cassat, M.D., Ph.D.
Vanderbilt University School of Medicine
The contribution of host and pathogen to altered bone homeostasis and bacterial survival during osteomyelitis

Kevin Jon Cheung, M.D.
Johns Hopkins University
Elucidating the role of K14+ leader cells in breast cancer invasion and metastasis

Ethan Michael Goldberg, M.D., Ph.D.
University of Pennsylvania Perelman School of Medicine
Analysis of circuit function informs novel therapeutic interventions in an epilepsy model

Malay Haldar, M.D., Ph.D.
Washington University School of Medicine
Transcription factor SPI-C at the interface of iron homeostasis and innate immunity

Marcin Imielinski, M.D., Ph.D.
Harvard Medical School
Reconstructing complex loci in lung adenocarcinoma with large-insert whole genome sequencing

Jeffery M Klco, M.D., Ph.D.
University of Tennessee
Role of notch signaling in the bone marrow stroma

Jason Knight, M.D., Ph.D.
University of Michigan-Ann Arbor
Innate immunity in the pathogenesis of lupus and antiphospholipid vasculopathy

Anita Katherine McElroy, M.D., Ph.D.
Emory University School of Medicine
Defining the roles of CD4+ T cells in generating a protective immune response against Rift Valley fever virus

Sudarshan Rajagopal, M.D., Ph.D.
Duke University Medical Center
Dissecting receptor Signaling pathways in pulmonary hypertension

Sean Robinson Stowell, M.D., Ph.D.
Emory University School of Medicine
Elucidating mechanisms of innate immunity against molecular mimicry

2013

Susanne Elizabeth Ahmari, M.D., Ph.D.
Columbia University
Testing the Role of Cortico-Striatal Circuits in Obsessive Compulsive Disorder Pathology and Treatment

Gautam Bhave, M.D., Ph.D.
Vanderbilt University Medical Center
Role of Peroxidasin and Protein Halogenation in Diabetic Nephropathy

Ajai Arvind Dandekar, M.D., Ph.D.
University of Washington
Quorum sensing and mechanisms to ensure cooperation in the opportunistic pathogen Pseudomonas aeruginosa

Andrew Eugene Hermann Elia, M.D., Ph.D.
Harvard Medical School
Proteomic analysis of ubiquitination and protein stability in the DNA damage response

Gaorav P Gupta, M.D., Ph.D.
Memorial Sloan-Kettering Cancer Center
DNA Damage Responses in Breast Cancer Pathogenesis

Andrew Caleb Hsieh, M.D.
University of California-San Francisco
Elucidating the role of aberrant translational control on prostate cancer invasion and metastasis

Jean-Sebastien Joyal, M.D., Ph.D.
University of Montreal Faculty of Medicine
Neuronal Energy Metabolism Drives Angiogenesis

Alex Kentsis, M.D., Ph.D.
Harvard Medical School
Tumorigenesis by endogenous DNA transposons in human cancer.

Jeniel Emily Nett, M.D., Ph.D.
University of Wisconsin-Madison
Mechanisms of Candida Biofilm Immune Evasion

Rhea Myers Sumpter, Jr., M.D., Ph.D.
University of Texas Southwestern Medical Center-Dallas
A novel role for FANCC in selective autophagy

2012

Chetan Bettegowda, M.D., Ph.D.
Johns Hopkins University
Translational molecular profiling of oligodendrogliomas

Scott Richard Floyd, M.D., Ph.D.
Massachusetts Institute of Technology
Insulating chromatin from DNA damage signaling: epigenetic modifications and connections to human cancer

Benjamin Elison Gewurz, M.D., Ph.D.
Harvard Medical School
Identification of novel NFkB pathway components important for lymphomagenesis

Michael Rosenblum, M.D., Ph.D.
University of California-San Francisco
Memory regulatory T cells in inflammatory and autoimmune disease

Michael Thomas Spiotto, M.D., Ph.D.
University of Chicago
Identification of chromosomal aberrations that cooperate with the human papillomavirus to cause cancer

David Tsai Ting, M.D.
Harvard Medical School
Characterization of non-coding RNAs in pancreatic adenocarcinoma

Richard Chih-Chien Wang, M.D., Ph.D.
University of Texas Southwestern Medical Center-Dallas
Akt-mediated regulation of autophagy & tumorigenesis through formation of a beclin 1/keratin intermediate filament complex

Kelley Yan, M.D., Ph.D.
Stanford University
Regulation of active and quiescent intestinal stem cells

Ellen Yeh, M.D., Ph.D.
Stanford University
Function of the plastid organelle in P. falciparum: beyond isoprenoid precursor biosynthesis and blood stage

Hao Zhu, M.D.
Harvard University
Investigating the Lin28/let-7 pathway in mouse models of liver cancer and regeneration

2011-2007