2013
2012
2011
2009
2008
2007
2006
2005
2003
2002
2013
Dustin Brisson, Ph.D.
University of Pennsylvania,
Evolution of original antigenic sin in lyme disease
Michael Federle, Ph.D.
University of Illinois-Chicago
Signal jamming of bacterial pathogens as an antivirulence strategy
Xiarong Lin, Ph.D.
Texas A&M University
Fungal communication and pathogenicity
Suzanne Noble, M.D., Ph.D.
University of California-San Francisco
Discovery of a cell type switch that drives fungal-mammalian commensalism
Sara Sawyer, Ph.D.
University of Texas-Austin
Genetics of viral species tropism
Emily Troemel, Ph.D.
University of California-San Diego
Microsporidia virulence factors exploit host cell physiology
David Weiss, Ph.D.
Emory University
Novel RNAi-like system controls bacterial innate immune evasion and virulence
Felix Yarovinsky, M.D.
University of Texas Southwestern Medical Center
A new arm of innate immunity: TLR-independent neutrophil-IFN-gamma in host protection against microbial infection
Liang Zhou, M.D., Ph.D.
Northwestern University
Environmental impact on host-pathogen interaction
2012
Neal M. Alto, Ph.D.
University of Texas Southwestern Medical Center
Systems architecture of bacterial effector/host membrane interactions
Anna I. Bakardjiev, M.D.
University of California-San Francisco School of Medicine
Pregnancy-related pathogenicity determinants of Listeria monocytogenes
Juliane Bubeck Wardenburg, M.D., Ph.D.
University of Chicago
Tuning of the host-bacterial interaction by a pore-forming toxin
Carolyn B. Coyne, Ph.D.
University of Pittsburgh School of Medicine
Actin cytoskeleton and antiviral innate immune signaling
Sarah M. Fortune, M.D.
Harvard University
Quick change: polarity, diversity and virulence in Mycobacterium tuberculosis
Chyi-Song Hsieh, M.D., Ph.D.
Washington University School of Medicine
Host discrimination between pathogenic and commensal bacteria in the colon
Jonathan C. Kagan, Ph.D.
Harvard Medical School
Novel approaches to study RIG-I like receptor mediated antiviral immunity
Julie K. Pfeiffer, Ph.D.
University of Texas Southwestern Medical Center
How gut microbes enhance enteric virus infectivity
Christopher S. Sullivan, Ph.D.
University of Texas-Austin
Herpes virus immune evasion via non-coding RNA regulatory elements
Sing Sing Way, M.D., Ph.D.
University of Minnesota Medical School
Maternal regulatory T cells control the immune pathogenesis of prenatal infection
2011
David M. Aronoff, M.D.
University of Michigan-Ann Arbor
Prostaglandin E2 synthesis and signaling in the pathogenesis of puerperal Group A Streptococcus infections
Gregory M. Barton, Ph.D.
University of California-Berkeley
Interactions between TLRs and intracellular pathogens
Julie Magarian Blander, Ph.D.
Mount Sinai School of Medicine
Innate immune recognition of vita-PAMPs: a new class of pathogen associated molecular patterns that signifies microbial viability
Sara R. Cherry, Ph.D.
University of Pennsylvania
Systems biology of Alphavirus infection
Jonathan Dworkin, Ph.D.
Columbia University
Characterization of a novel family of receptors mediating metazoan recognition of microbes
Ekaterina Heldwein, Ph.D.
Tufts University School of Medicine
Structural mechanism of herpes virus egress
Sarkis K. Mazmanian, Ph.D.
California Institute of Technology
Novel probiotic therapy for microbial infections
Joseph D. Mougous, Ph.D.
University of Washington
Breaching the commensal barrier to infection with type VI secretion
Justin L. Sonnenburg, Ph.D.
Stanford University School of Medicine
Mechanisms of intestinal microbiota-conferred protection from enteric pathogens
Benjamin R. tenOever, Ph.D.
Mount Sinai School of Medicine
Small RNA-mediated control of microbes
2009
Jen-Tsan Ashley Chi, M.D., Ph.D.
Duke University Medical Center
Sequence determinant of the Plasmodium falciparum gene regulation by human microRNAs
K. Heran Darwin, Ph.D.
New York University School of Medicine
Ubiquitin-like proteins in bacterial pathogens
Denise Monack, Ph.D.
Stanford University
Host-pathogen interactions during persistent Salmonella infection
Maya Saleh, Ph.D.
McGill University
Regulation and molecular mechanisms of NLR-mediated innate immunity
Erica O. Saphire, Ph.D.
Scripps Research Institute
Arenavirus GP: architecture, receptor binding sites, and immune recognition
Russell Vance, Ph.D.
University of California-Berkeley
Innate immune cytosolic immunosurveillance pathways for sensing bacterial pathogens
2008
David Artis, Ph.D.
University of Pennsylvania
Tracking helminth-specific immune responses in vivo
Richard Bennett, Ph.D.
Brown University
Phenotypic variation and host adaptation by the human fungal pathogen Candida albicans
Miriam Braunstein, Ph.D.
University of North Carolina-Chapel Hill
Identification of in vivo-secreted proteins of Mycobacterium tuberculosis with roles in host-pathogen interactions
James Carlyle, Ph.D.
University of Toronto
MHC-independent recognition of infected cells by natural killer cells of the innate immune system
Stephen Girardin, Ph.D.
University of Toronto
The Nod-like receptor Nod9 links mitochondrial dynamics and innate immunity to bacterial pathogens
Chuan He, Ph.D.
University of Chicago
How Staphylococcus aureus senses host immune defenses
Kent L. Hill, Ph.D.
University of California-Los Angeles
Cell-cell communication and social motility in pathogenesis and development of African trypanosomes
D. Borden Lacy, Ph.D.
Vanderbilt University Medical Center
Structural mechanisms of Heliobacter pylori pathogenesis
John MacMicking, Ph.D.
Yale University School of Medicine
Immune control of human phagosomal pathogens by a novel GTPase superfamily
Adrie J.C. Steyn, Ph.D.
University of Alabama-Birmingham
Carbon monoxide and Mycobacterium tuberculosis persistence
Timothy L. Tellinghuisen, Ph.D.
The Scripps Research Institute
Subversion of a host kinase and vesicle trafficking components for the production of infectious hepatitis C virus
David Wang, Ph.D.
Washington University School of Medicine
A genomics-based approach to novel viral etiologies of diarrhea
Marvin Whiteley, Ph.D.
University of Texas-Austin
Mechanistic insight into host modulation of bacterial group activities
Dong Yu, Ph.D.
Washington University School of Medicine
Modulation of the DNA damage response by human cytomegalovirus
2007
Benjamin K. Chen, M.D., Ph.D.
Mount Sinai School of Medicine
Dissemination of HIV through virological synapses
Andrew Darwin, Ph.D.
New York University School of Medicine
Mechanisms of Pseudomonas aeruginosa tolerance to secretin-induced stress during host infection
Michael R. Farzan, Ph.D.
Harvard Medical School
Parallel identification of obligate viral receptors
Britt Glaunsinger, Ph.D.
University of California-Berkeley
Global modulation of cellular gene expression by an oncogenic human herpesvirus
Karen J. Guillemin, Ph.D.
University of Oregon
Regulation of gut epithelial cell homeostasis by the microbiota
Lora V. Hooper, Ph.D.
University of Texas Southwestern Medical Center
Innate immune responses to commensal bacteria at gut epithelial surfaces
Eckhard Jankowsky, Ph.D.
Case Western Reserve University
Molecular mechanisms of pathogen identification by the pattern recognition receptors RIG-I and MDA5
Barbara I. Kazmierczak, M.D., Ph.D.
Yale University
The role of injury in Pseudomonas aeruginosa pulmonary infection
Manuel Llinas, Ph.D.
Princeton University
Global analysis of the Plasmodium falciparum metabolome
Harmit S. Malik, Ph.D.
University of Washington
Evolution-based identification and functional study of intracellular host-virus interactions
Dorian B. McGavern, Ph.D.
The Scripps Research Institute
Chemical and molecular approaches to probe viral pathogenesis in real time
Yorgo Modis, Ph.D.
Yale University
Cell entry and innate immune recognition of flaviviruses
Neal Silverman, Ph.D.
University of Massachusetts Medical School
Intracellular bacterial recognition in the Drosophila innate immune response
Raphael H. Valdivia, Ph.D.
Duke University Medical Center
The role of secreted bacterial proteases in chlamydial pathogenesis
Andres Vazquez-Torres, D.V.M., Ph.D.
University of Colorado-Denver and Health Sciences Center-Fitzsimons Campus
Effects of nitrosative stress on bacterial two component regulatory systems in innate host defense
Ning Zheng, Ph.D.
University of Washington
Viral hijacking of host ubiquitin ligase machinery
2006
Choukri Ben Mamoun, Ph.D.
University of Connecticut Health Center
Function and regulation of host and parasite nutrient transporters during malaria infection
Helen E. Blackwell, Ph.D.
University of Wisconsin-Madison
Interception of bacterial quorum sensing with synthetic ligands
Blossom Damania, Ph.D.
University of North Carolina-Chapel Hill
Role of viral signaling proteins in the pathogenesis of Kaposi's sarcoma-associated herpes virus (KSHV)
Manoj T Duraisingh, Ph.D.
Harvard School of Public Health
Epigenetic control of virulence gene expression in Plasmodium falciparum
Peter J. Espenshade, Ph.D.
Johns Hopkins University School of Medicine
Oxygen-sensing and adaptation to host tissue hypoxia in the human fungal pathogen Cryptococcus neoformans
Robert F. Kalejta, Ph.D.
University of Wisconsin-Madison
Cellular and viral determinants of human cytomegalovirus lytic and latent replication cycles
Christian Munz, Ph.D.
Rockefeller University
Regulation of macroautophagy by viral infection
Kim Orth, Ph.D.
University of Texas Southwestern Medical Center
VopL, a Vibrio effector that nucleates actin
Ana Rodriguez, Ph.D.
New York University School of Medicine
The role of hypoxanthine degradation in malaria-induced pathogenesis
Karla Fullner Satchell, Ph.D.
Northwestern University
A mouse model for the role of toxins in cholera pathogenesis
Luis M Schang, D.V.M., Ph.D.
University of Alberta
Silencing and antisilencing in the regulation of viral gene expression
Eric Skaar, Ph.D.
Vanderbilt University Medical Center
In vivo identification of Staphylococcus aureus proteins that defend against host neutrophils
Vanessa Sperandio, Ph.D.
University of Texas Southwestern Medical Center
Interkingdom signaling in bacterial pathogenesis
Billy Tsai, Ph.D.
University of Michigan Medical School
How cholera toxin hijacks cellar machineries to transport across the ER membrane?
2005
Jody L. Baron, M.D., Ph.D.
University of California-San Francisco School of Medicine
Understanding immunopathogenesis of Hepatitis B virus
Matthew S. Bogyo, Ph.D.
Stanford University School of Medicine
Chemical mapping of proteolytic networks involved in Toxoplasma gondii pathogenesis
John H. Brumell, Ph.D.
University of Toronto
Recognition of bacteria in the cytosol of mammalian cells by protein conjugation systems
Tatjana Dragic, Ph.D.
Albert Einstein College of Medicine of Yeshiva University
Entry and intracellular trafficking of Hepatitis C virus
Michael S. Glickman, M.D.
Memorial Sloan-Kettering Cancer Center
Regulated intramembrane proteolysis in controlling Mycobacterium tuberculosis virulence and cell envelope composition
Akiko Iwasaki, Ph.D.
Yale University
Stromal cell contributions in innate and adaptive immune responses to mucosal viral infection
John S. Parker, B.V.M.S., Ph.D.
Cornell University College of Veterinary Medicine
Reovirus-induced apoptosis: the role of the viral outer-capsid protein mu1
Lalita Ramakrishnan, M.D., Ph.D.
University of Washington School of Medicine
Forward genetic screens in the zebrafish to identify host determinants of susceptibility to tuberculosis
Gregory A. Smith, Ph.D.
Northwestern University Feinberg School of Medicine
Coordination of herpes virus assembly and transport in axons of sensory neurons
Linda F. van Dyk, Ph.D.
University of Colorado Health Sciences Center
Analyzing tumor suppressors in the control of virus infection and inflammation
Sean P. Whelan, Ph.D.
Harvard Medical School
Exploration of the interaction of RNA viruses with their host cells
2003
David C. Bloom, Ph.D.
University of Florida College of Medicine
Identification of neuron-specific factors that regulate HSV-1 chromatin structure and transcription during latency
Dana A. Davis, Ph.D.
University of Minnesota-Twin Cities
Control of phenotypic switching and pathogenesis by the Mds3 protein
David A. Fidock, Ph.D.
Albert Einstein College of Medicine of Yeshiva University
Plasmodium falciparum transmembrane proteins and their role in parasite susceptibility to heme-binding antimalarials
Michael J. Gale, Jr. Ph.D.
University of Texas Southwestern Medical Center
Control of hepatitis C virus replication
Andrew S. Neish, M.D.
Emory University School of Medicine
Transgenic analysis of prokaryotic effector proteins in the eukaryote, Drosophila melanogaster
Eric J. Rubin, M.D., Ph.D.
Harvard School of Public Health
Cell signaling by bacterial cytokines in Mycobacterium tuberculosis
Wenqing Xu, Ph.D.
University of Washington School of Medicine
Innate immunity: how do Toll-like receptors recognize microbial pathogens?
Thomas C. Zahrt, Ph.D.
Medical College of Wisconsin
Mycobacterium tuberculosis regulators modulating reactivation
2002
Barbara A. Burleigh, Ph.D.
Harvard School of Public Health
Functional characterization of the role of the host cell fibrogenic response in Trypanosoma cruzi infection
Zhijian J. Chen, Ph.D.
University of Texas Southwestern Medical Center
Roles of TRAF5-regulated IKK activators in innate immunity
Maurizio Del Poeta, M.D.
Medical University of South Carolina-College of Medicine
Roles for inositol phosphoryl ceramide synthase 1 (IPC1) in fungal-host interaction
Heidi Goodrich-Blair, Ph.D.
University of Wisconsin-Madison
Pathogenesis of Xenorhabdus nematophilus in insects: a model for the innate immune response to bacterial pathogens
David B. Haslam, M.D.
Washington University-School of Medicine
Mechanisms of Shiga toxin translocation and intoxication within host cells
Margarethe (Meta) J. Kuehn, Ph.D.
Duke University Medical Center
Toxin trafficking via vesicles
C. Erec Stebbins, Ph.D.
Rockefeller University
Structural studies of bacterial virulence factors
Ren Sun, Ph.D.
University of California-Los Angeles-School of Medicine
Identification of cellular factors that determine the fate of herpes virus infection: latency versus lytic replication
Chloe L. Thio, M.D.
Johns Hopkins University School of Medicine
The identification of human genes associated with hepatitis B virus outcomes