Investigators in the Pathogenesis of Infectious Disease

Grant Recipients

2016
2015
2014
2013
2012

2011-2002 Recipients
 

2016

Jörn Coers, D.Phil., Ph.D.
Duke University
Host-mediated lysis of cytoplasmic pathogens

Min Dong, Ph.D.
Harvard Medical School
Host factors conferring susceptibility to Clostridium difficile toxins

Christine M. Dunham, Ph.D.
Emory University School of Medicine
Characterization of pathways involved in bacterial persistence and antibiotic resistence

Nels C. Elde, Ph.D.
University of Utah
A new class of retrogenes modulating pathogenesis

Scott E. Hensley, Ph.D.
University of Pennsylvania
Effect of maternal antibodies on the neonatal immune response to influenza virus

Audrey R. Odom, M.D., Ph.D.
Washington University
Insights into the chemical ecology of malaria parasites

Alexander Ploss, Ph.D.
Princeton University
Breaking species barriers of human hepatotropic pathogens

Amariliz Rivera, Ph.D.
Rutgers University-Rutgers Biomedical and Health Sciences-New Jersey Medical School
Mechanisms of bidirectional innate cell licensing in antifungal immunity

Sunny Shin, Ph.D.
University of Pennsylvania Perelman School of Medicine
Overcoming pathogen-mediated translation inhibition to enable robust immune defense

Joseph C. Sun, Ph.D.
Memorial Sloan-Kettering Cancer Center
Natural killer cell control of cytomegalovirus infection
 

2015

Jesse D. Bloom, Ph.D.
University of Washington
Understanding the stochasticity of viral infection at the level of single cells 

Igor E. Brodsky, Ph.D.
University of Pennsylvania
The role of chemokine-chemokine receptor interactions in anti-bacterial protective immunity

Ken Cadwell, Ph.D.
New York University School of Medicine
Gene-microbe interactions in inflammatory bowel disease

Matthew James Evans, Ph.D.
Icahn School of Medicine at Mount Sinai
Determinants of hepatitis C virus persistence

Andrew L. Goodman, Ph.D.
Yale University
Understanding pathogen-commensal interaction in the earliest stages of infection

Elissa A. Hallem, Ph.D.
University of California-Los Angeles
Thermosensation in skin-penetrating parasitic nematodes

Sun Hur, Ph.D.
Harvard Medical School
Mechanism for dsRNA-dependent and -independent activation of the antiviral gene, PKR

Rahul Manu Kohli, M.D., Ph.D.
University of Pennsylvania
Tuning evolution and antibiotic resistance by modulating the SOS pathway

Li-Jun Ma, Ph.D.
University of Massachusetts-Amherst 
Supernumerary chromosomes and pathogenicity of opportunistic fungal infections

Luciano A. Marraffini, Ph.D.
Rockefeller University
Effect of type III CRISPR-Cas immunity on phage-mediated staphylococcal pathogenesis

Daniel Mucida, Ph.D.
Rockefeller University
Adaptation of immune cells to the gut tissue: consequences for immunity and tolerance

Nan Yan, D.Phil.
University of Texas Southwestern Medical Center-Dallas
STING activation at the nexus of microbial infection and host innate immunity
 

2014

Robert A. Cramer, Ph.D.
Dartmouth College
Bioenergetics and microbial pathogenesis sufficiency

Michael A.  Fischbach, Ph.D.
University of California-San Francisco
Novel microbiota-derived molecules that modulate the host immune response

De'Broski R. Herbert, Ph.D.
University of California-San Francisco
Trefoil factor proteins modulate host immunity against hookworms

Tobias M. Hohl, M.D., Ph.D.
Memorial Sloan-Kettering Cancer Center
Tracing innate control over respiratory and systemic fungal infection

Alexei V. Korennykh, Ph.D.
Princeton University
Systems analysis of pathogen defense mediated by 2', 5'-linked isoRNA

Matthias Marti, Ph.D.
Harvard University
Cellular communication in malaria parasites

Erika L. Pearce, D.Phil., Ph.D.
Washington University
Cellular metabolism in immunity to infection

Manuela Raffatellu, M.D.
University of California-Irvine
Characterization of novel populations of neutrophils during bacterial infection

Daniel B. Stetson, Ph.D.
University of Washington
Why do DNA viruses cause cancer?

Niraj H. Tolia, Ph.D.
Washington University School of Medicine
Molecular basis for and inhibition of red blood cell invasion by Plasmodium parasites

Victor J. Torres, Ph.D.
New York University School of Medicine
Staphylococcus aureus pore-forming toxins: leukocyte killing and beyond

Robert T.  Wheeler, Ph.D.
University of Maine
Phagocytes block fungal dimorphism to defend the epithelial barrier

2013

Abraham Brass, M.D., Ph.D.
University of Massachusetts Medical School
Defining dengue virus’s dependencies: discovery and characterization of host factors required for viral replication

Dustin Brisson, Ph.D.
University of Pennsylvania
Evolution of original antigenic sin in lyme disease

Michael Federle, Ph.D.
University of Illinois-Chicago
Interspecies communication among commensal and pathogenic bacteria

Xiarong Lin, Ph.D.
Texas A&M University
Fungal communication and pathogenicity

Suzanne Noble, M.D., Ph.D.
University of California-San Francisco
Discovery of a cell type switch that drives fungal-mammalian commensalism

Sara Sawyer, Ph.D.
University of Texas-Austin
Genetics of viral species tropism

Emily Troemel, Ph.D.
University of California-San Diego
Microsporidia virulence factors exploit host cell physiology

David Weiss, Ph.D.
Emory University
Novel RNAi-like system controls bacterial innate immune evasion and virulence

Felix Yarovinsky, M.D.
University of Texas Southwestern Medical Center
TLR-independent host resistance to protozoan parasites

Liang Zhou, M.D., Ph.D.
Northwestern University
Environmental impact on host-pathogen interaction

2012

Neal M. Alto, Ph.D.
University of Texas Southwestern Medical Center
Systems architecture of bacterial effector/host membrane interactions

Anna I. Bakardjiev, M.D.
University of California-San Francisco School of Medicine
Pregnancy-related pathogenicity determinants of Listeria monocytogenes

Juliane Bubeck Wardenburg, M.D., Ph.D.
University of Chicago
Tuning of the host-bacterial interaction by a pore-forming toxin

Carolyn B. Coyne, Ph.D.
University of Pittsburgh School of Medicine
Actin cytoskeleton and antiviral innate immune signaling

Sarah M. Fortune, M.D.
Harvard University
Quick change: polarity, diversity and virulence in Mycobacterium tuberculosis

Chyi-Song Hsieh, M.D., Ph.D.
Washington University School of Medicine
Host discrimination between pathogenic and commensal bacteria in the colon

Jonathan C. Kagan, Ph.D.
Harvard Medical School
Novel approaches to study RIG-I like receptor mediated antiviral immunity

Julie K. Pfeiffer, Ph.D.
University of Texas Southwestern Medical Center
How gut microbes enhance enteric virus infectivity

Christopher S. Sullivan, Ph.D.
University of Texas-Austin
Herpes virus immune evasion via non-coding RNA regulatory elements

Sing Sing Way, M.D., Ph.D.
University of Minnesota Medical School
Maternal regulatory T cells control the immune pathogenesis of prenatal infection