Note: This list reflects the awardees' original grant institution.
2013
2012
2011
2009
2008
2007
2006
2005
2003
2002
2013
Gregory R. Bowman, Ph.D.
University of California-Berkeley
Decrypting cryptic allosteric sites resulting from protein flexibility
Yaniv Erlich, Ph.D.
Whitehead Institute for Biomedical Research
Dissecting complex phenotypes using web 2.0 social networks
Stephanie I. Fraley, Ph.D.
Johns Hopkins University School of Medicine
Digitizing microRNA: integrated profiling and discovery for rapid, quantitative, and broad-scale detection in infectious disease
Hernan G. Garcia, Ph.D.
Princeton University
Wiring up the synthetic fly
Karen E. Kasza, Ph.D.
Memorial Sloan-Kettering Cancer Center
Mechanical cues coordinating cell behaviors during morphogenesis
Gabriel Kwong, Ph.D.
Massachusetts Institute of Technology
Nanoparticles that amplify biomarkers in vivo for ultrasensitive metastasis monitoring
Megan N. McClean, Ph.D.
Princeton University
Optogenetic and microfluidic tools for generating dynamic inputs to interrogate and control biological networks
Mikhail G. Shapiro, Ph.D.
University of California-Berkeley
Genetically encoded reporters for sensitive non-invasive imaging of biological function
Paul A. Sigala, Ph.D.
Washington University
Mechanistic probes of heme metabolism in malaria parasites
Bo Wang, Ph.D.
University of Illinois-Urbana-Champaign
In vivo imaging and functional genomic analysis of stem cells in human parasitic worm schistosoma
2012
Buz M. Barstow, Ph.D.
Harvard Medical School
Evolving the limits of metabolism and in vivo catalysis
ShiNung Ching, Ph.D.
Harvard Medical School
Massachusetts General Hospital
Towards treatments in disorders of consciousness and new models of general anesthesia
Kwanghun Chung, Ph.D.
Stanford University
Clear, Lipid-exchanged, Anatomically Rigid, Imaging/immunostaining-compatible, Tissue hYdrogel (CLARITY) technology for high-throughput and high-content whole tissue analysis
Robert Gregg, Ph.D.
Northwestern University
From machine to biomimetic control in robot-assisted walking
Maureen E. Hillenmeyer, Ph.D.
Stanford University
In vivo synthetic evolution of bioactive natural products
Allon Moshe Klein, Ph.D.
Harvard Medical School
Defining patterns and mechanisms of stem cell fate choice
Sergey A. Kryazhimskiy, Ph.D.
Harvard University
Predicting evolution in microbial populations
Heather J. Kulik, Ph.D.
Stanford University
Deciphering the role of the protein scaffold in enzyme catalysis with fast and accurate computation
Lulu Qian, Ph.D.
California Institute of Technology
Exploring and re-realizing the principles of information processing in biology using artificial nucleic-acid systems
Jesse G. Zalatan, Ph.D.
University of California-San Francisco
Entropic contributions to efficiency in biochemical networks
2011
Paul C. Blainey, Ph.D.
Stanford University
From single cells to populations: using microfluidics, genomics, and culture to better understand infectious disease in the post-genomic era
L. Stirling Churchman, Ph.D.
University of California-San Francisco
Regulation of the RNA polymerase motor mechanism in vivo
Shawn M. Douglas, Ph.D.
Harvard Medical School
Self-assembled DNA devices for nanoscale manipulation of immune signal transduction
Keisuke Goda, Ph.D.
University of California-Los Angeles
Development of high-throughput blood screening technology for real-time noninvasive cancer diagnostics and therapy
Christopher D. Harvey, Ph.D.
Princeton University
Neural circuit mechanisms underlying decision-making in mice
Alan Horsager, Ph.D.
University of Southern California
Using genetically-targeted neural modulation to examine retinal circuits and restore vision in the blind
Eleni Katifori, Ph.D.
Rockefeller University
Robustness and optimality in loopy biological distribution networks
Tobias J. D. Reichenbach, Ph.D.
Rockefeller University
Low-frequency hearing in mammals
Eva-Maria Schoetz, Ph.D.
Princeton University
Biophysical approaches to study stem cell dynamics during regeneration in planarians
Jonathan R. Silva, Ph.D.
Washington University
Applying molecular spectroscopy to derive multi-scale cardiac bioelectricity models
2009
Julie S.Biteen, Ph.D.
Stanford University
Superresolution imaging in live cells using single-molecule active-control microscopy
Ofer Feinerman, Ph.D.
Sloan-Kettering Institute for Cancer
Cellular heterogeneity and cooperativity shape decision-making in the immune system
Surya Ganguli, Ph.D.
University of California-San Francisco
The expression and acquisition of sequence memory in neuronal networks
Mark A. Kramer,Ph.D.
Boston University
Population rhythms of epilepsy
Michael Rust, Ph.D.
Harvard University
Nonlinear dynamics underlying the cyanobacterial circadian clock
Daniel A. Wagenaar,Ph.D.
California Institute of Technology
Neural circuitry and mechanisms of multisensory integration in a predatory invertebrate
2008
Dirk R. Albrecht, Ph.D.
Rockefeller University
Investigating neural circuits governing chemotaxis using microtechnology
David Biron, Ph.D.
Brandeis University
Understanding small neural circuits
Lynette Cegelski, Ph.D.
Washington University
Mapping the structural and functional landscape of the microbial extracellular matrix
Rhiju Das, Ph.D.
University of Washington
High resolution prediction of new RNA folds
Alfredo Dubra-Suarez, Ph.D.
University of Rochester
Understanding glaucoma through structural and functional in vivo cellular imaging of the retina
Alexander Dunn, Ph.D.
Stanford University
Single molecule characterization of the energetic landscape underlying myosin force generation
Maria N. Geffen, Ph.D.
Rockefeller University
Perception and neural encoding of textured sounds
Andrea M. Goforth, Ph.D.
University of California-Davis
Bimodal, luminescent/magnetic nanoparticle assemblies targeted to alpha-4-beta-1 integrin for tumor imaging and therapy
Ming Hammond, Ph.D.
Yale University
Large-scale discovery and analysis of regulatory RNAs using computational and chemical approaches
Arjun Raj, Ph.D.
Massachusetts Institute of Technology
Stochastic gene expression in development: from phenomena to function
Sridevi V. Sarma, Ph.D.
Massachusetts Institute of Technology
Improved therapies for Parkinson’s disease using advanced engineering methods
Georg Seelig, Ph.D.
California Institute of Technology
Nucleic acid logic circuits for conditional gene regulation
Jan Skotheim, Ph.D.
Rockefeller University
A systems level approach to cell cycle control: from molecules to motifs to physiology
Joshua Vaughan, Ph.D.
Harvard University
Discovery of new motility mechanism and high speed, in vivo imaging of motor protein dynamics
Lauren J. Webb, Ph.D.
Stanford University
Electrostatic fields at the protein-protein interface
2007
Derek Cummings, Ph.D.
Johns Hopkins University
Natural and vaccine-induced immunity and spatiotemporal dynamics of epidemic dengue
Ajit P. Joglekar, Ph.D.
University of North Carolina-Chapel Hill
Building a mechanistic model of the structure and function of a kinetochore-microtubule attachment
Harold D. Kim, Ph.D.
Harvard University
Understanding the mechanisms of sensitivity in gene expression
Gavin McLean King, Ph.D.
University of Colorado-Boulder
The dynamic structural biology of ion channel proteins: an ultra-stable atomic force microscope study
Mary L. Kraft, Ph.D.
Stanford University
Composition analysis of the influenza virus pre-envelope by multiple isotope imaging mass spectrometry (MIMS)
Alison L. Marsden, Ph.D.
Stanford University
Engineering new treatments for cardiovascular disease via optimal design and physiologic simulation
Celeste M.Nelson, Ph.D.
University of California-Berkeley
Biophysical dynamics in the regulation of tissue morphogenesis
Erin C. Rericha, Ph.D.
University of Maryland-College Park
Fluid flows in cell mechanosensitivity and cell motion
Jason T.Ritt, Ph.D.
Massachusetts Institute of Technology
Active sensing in natural and robotic organisms
Alexander Sher, Ph.D.
University of California-Santa Cruz
Investigation of retinal processing through large-scale multi-electrode recordings
Joshua S.Weitz, Ph.D.
Princeton University
Evolutionary ecology of bacterial viruses
Ahmet Yildiz, Ph.D.
University of California-San Francisco
Molecular mechanism of dynein in vitro and in living cells
2006
Jason Brujic, Ph.D.
Columbia University
Mechanical networks in biology: from proteins to cells
Nicolas E. Buchler, Ph.D.
Rockefeller University
Gene duplication and the evolution of function in regulatory networks
Margaret L. Gardel, Ph.D.
Scripps Research Institute
Dynamic force generation in cell migration
Daniel I. Goldman, Ph.D.
University of California-Berkeley
Dynamic locomotion on challenging substrates
Edo L. Kussell, Ph.D.
Rockefeller University
Evolution of microbial physiologies
Laura A. Miller,Ph.D.
University of Utah
Developmental and evolutionary biofluid dynamics: case studies in locomotion and heart development
Dana Pe’er, Ph.D.
Harvard Medical School
A systems approach to elucidate integration of signal and decision in cells
Aviv Regev, Ph.D.
Harvard University
From modules to mechanisms: the function and evolution of molecular networks
Eric Shea-Brown, Ph.D.
New York University
Neurobiological dynamics of timing and decisions
Hadley D. Sikes, Ph.D.
University of Colorado-Boulder
Well-defined, supramolecular assemblies of redox enzymes via templated self-assembly for use in mechanistic electron transport studies and targeted apoptosis
2005
Emre Aksay, Ph.D.
Princeton University
Neural mechanisms for control of eye position
Rachel Brem, Ph.D.
University of Washington
The genetics of transcription in budding yeast
Yann R. Chemla, Ph.D.
University of California-Berkeley
Single-molecule study of bacteriophage DNA packaging and mitochondrial protein import
Oksana Cherniavskaya, Ph.D.
Columbia University
Exploring the spatial interactions in cytoskeletal proteins using nanoscale bioarrays
Timothy J. Gardner, Ph.D.
Massachusetts Institute of Technology
Tracking neural programs for song
Robert H. Havlin, Ph.D.
National Institutes of Health
Snapshots of proteins in action: elucidating freeze-trapped intermediates with solid state nuclear magnetic resonance
Christine E. Heitsch, Ph.D.
University of Wisconsin-Madison
Combinatorial and computational approach to deciphering the biological information encoded by single-stranded nucleotide sequences
Joshua B. Plotkin, Ph.D.
Harvard University
Novel methods to compute selection pressures on proteins at the genome-wide scale
Astrid A. Prinz, Ph.D.
Emory University
Models of activity-dependent homeostatic regulation in neural networks on the basis of brute force exploration of high-dimensional parameter spaces
Benjamin J.Raphael, Ph.D.
University of California-San Diego
High-resolution analysis of tumor genome architectures
Megan T. Valentine, Ph.D.
Stanford University
Establishing the mechanism of kinesin processivity
2003
Lindsay G. Cowell, Ph.D.
Duke University Medical Center
A novel statistical approach to deducing the function of regulatory DNA: examples from analyses of recombination signal sequences
Adrienne L. Fairhall, Ph.D.
Princeton University
Neural computation, adaptation and information processing
Jeffrey R. Kuhn, Ph.D.
Yale University
Total internal reflection fluorescence microscopy observations of actin branching dynamics in vivo
Jason K. Sello, Ph.D.
Harvard Medical School
Taking a chemical genetic scalpel to a Streptomyces colony
Ryohei Yasuda, Ph.D.
Cold Spring Harbor Laboratory
Visualization of biochemical signaling in single dendritic spines
Matthew A. Young, Ph.D.
University of California-Berkeley
Allosteric regulation in cell-signaling proteins
Muhammad N. Yousaf, Ph.D.
Harvard Medical School
A surface chemistry and materials approach to develop model substrates to study PI(4,5)P2 lipid raft dependent actin polymerization
2002
Michael B. Elowitz, Ph.D.
Rockefeller University
In vivo modeling: a synthetic approach to regulatory networks
Lisa J. Lapidus, Ph.D.
National Institutes of Health
Dynamics of polypeptides from measurement of intramolecular contact formation
Patrick W. Nelson, Ph.D.
University of Michigan
A theoretical study of HIV-1 pathogenesis: from primary infection, through latency, to effective drug therapy or progression to AIDS
Todd E. Peterson, Ph.D.
University of Arizona
Ultrahigh-resolution in vivo imaging
Jianghong Rao, Ph.D.
University of California-Los Angeles
Imaging gene expression and protein phosphorylation in living organisms
Ronald S. Rock, Jr., Ph.D.
Stanford University
Exploring the protein folding energy landscape at the single molecule level
Brent R. Stockwell, Ph.D.
Massachusetts Institute of Technology
Whitehead Institute for Biomedical Research
Chemical profiling of cellular disease states
Keith R. Weninger, Ph.D.
Stanford University
Single molecule study of the role of SNARE protein-assisted membrane fusion in calcium-triggered neurotransmitter release