Career Awards for Medical Scientists
Grant Recipients
2009
Chester Drum, M.D., Ph.D.
Massachusetts Institute of Technology
Protein nanoparticles for small molecule drug delivery
Pradipta Ghosh, M.D.
University of California-San Diego
Modulation of G-protein activity during oncogenic and metastatic progression
Matthew Vander Heiden, M.D., Ph.D.
Harvard Medical School
Metabolic control of cancer cell proliferation by pyruvate kinase M2
Quyen T. Nguyen, M.D., Ph.D.
University of California-San Diego
Testing surgery guided by molecular fluorescence imaging
Ann Zovein, M.D.
University of California-Los Angeles
Hemogenic endothelium: hematopoietic stem cell emergence from the vasculature
2008
Antonios O. Aliprantis, M.D., Ph.D. Kathleen H. Burns, M.D., Ph.D. Daniel Cahill, M.D., Ph.D. Alice Siau-In Chen-Plotkin, M.D. Sandeep Robert Datta, M.D., Ph.D. Joseph Alexander Duncan, M.D., Ph.D. Wendy Sarah Garrett, M.D., Ph.D. Jeffrey Parker Henderson, M.D., Ph.D. Lu Quang Le, M.D., Ph.D. Ravindra Majeti, M.D., Ph.D. Heather Christy Mefford, M.D., Ph.D. Ken Nakamura, M.D., Ph.D. Robert M. Plenge, M.D., Ph.D. David Tevis Pride, M.D., Ph.D. Miguel Nicolas Rivera, M.D. Agata Smogorzewska, M.D., Ph.D.
Harvard School of Public Health
Novel regulators of the osteoclast differentiation program
Johns Hopkins University
Role of retrotransposons in hematopoietic neoplasias
Harvard School of Public Health
Translational molecular genetic analyses of chemotherapeutic resistance in human brain tumors
University of Pennsylvania
Genomic approaches to frontotemporal dementia
Columbia University
Characterization of neural circuits that drive innate behaviors
University of North Carolina-Chapel Hill
Dissecting cryopyrin-mediated inflammatory signaling and its role in the pathogenesis of infectious diseases
Harvard School of Public Health
Novel effectors and regulators of inflammation, chronic infection, and carcinogenesis in the colon
Washington University
Iron acquisition by bacterial siderophores as a pathogenic determinant in urinary track infections
University of Texas Southwestern Medical Center-Dallas
Cell of origin and tumor microenvironment in NF1-associated neurofibroma development
Stanford University
Identification and targeting of human acute myeloid leukemia stem cell-specific cell surface molecules
University of Washington
Novel genomic rearrangements in developmental pediatric disorders
University of California-San Francisco
Physiologic and pathologic interactions of alpha-synuclein with mitochondria in Parkinson's disease
Harvard Medical School
Genotype-phenotype studies of rheumatoid arthritis susceptibility genes
Stanford University
Bacteriophage communities in oral health and disease
Harvard Medical School
Characterization of a novel X-linked tumor suppressor, WTX, in pediatric cancer
Harvard Medical School
Role of the Fanconi Anemia and other DNA crosslink repair pathways in genome maintenance and cancer prevention
2007
Jonathan Paul Alexander, M.D., Ph.D.
University of California-San Francisco
Isolation of a putative alveolar stem cell population and analysis of its role in development, maintenance, and repair of the lung epithelium
Robert Baloh, M.D., Ph.D.
Washington University
Mechanism of peripheral neuropathy from Mitofusin 2 mutations
James Elliott Bradner, M.D.
Harvard University
Design and characterization of highly potent inhibitors of HDAC6
Clark C. Chen, M.D., Ph.D.
Harvard Medical School
The molecular basis and therapeutic implications of genome instability during brain tumor progression
Arlene Dent, M.D., Ph.D.
Case Western Reserve University
Acquisition of immunity to blood stage Falciparum malaria in infants
Mahalia Sabrina Desruisseaux, M.D.
Albert Einstein College of Medicine of Yeshiva University
Neuroparasitology: neurological complications of cerebral malaria
Jay F. Dorsey, M.D., Ph.D.
University of Pennsylvania
Identification of mSin3b and Mad4 as novel p53 target genes directing p53-mediated transcriptional repression
Benjamin Levine Ebert, M.D., Ph.D.
Harvard Medical School
Genomic approaches to disorders of erythroid differentiation
Brian Todd Edelson, M.D., Ph.D.
Washington University
Macrophage and dendritic cell development
Rene L. Galindo, M.D., Ph.D.
University of Texas Southwestern Medical Center-Dallas
Genetic dissection of the Rhabdomyosarcoma initiator PAX-FKHR and PAX-related signaling in skeletal muscle development
Darnell Kaigler, D.D.S., Ph.D.
University of Michigan-Ann Arbor
Cell therapy for the treatment of alveolar bone defects
Michael Z. Lin, M.D., Ph.D.
University of California-San Diego
Elucidating mechanisms of synaptic plasticity and learning by visualizing and controlling local protein turnover
Roger Lo, M.D., Ph.D.
University of California-Los Angeles
Melanoma in the skin: initiation, progression, and crosstalk with dermal fibroblasts
Emanual Maverakis, M.D.
University of California-Davis
gC399tr an inhibitor of autoimmunity
Eric Matthew Morrow, M.D., Ph.D.
Harvard Medical School
Identification of autism genes in special founder populations using high-density SNP microarrays
Christopher Newton-Cheh, M.D.
Harvard Medical School
Genomic dissection of QT interval duration and sudden death
Dao Nguyen, M.D.
University of Washington
Stringent response in Pseudomonas aeruginosa biofilm formation and antibiotic tolerance
Anil Potti, M.D.
Duke University
Gene expression patterns coupled with signatures of oncogenic pathway deregulation provide a novel approach to targeted therapeutics in non-small cell lung carcinoma
Frank J. Probst, M.D., Ph.D.
Baylor College of Medicine
Generation of mouse models for X-linked diseases
Joseph C. Wu, M.D., Ph.D.
Stanford University
Molecular and cellular mechanisms of cardiac regeneration
Mark Nan Wu, M.D., Ph.D.
University of Pennsylvania
Identification of novel genes that regulate sleep in Drosophila melanogaster