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Scientific Disciplines

Infectious Disease

Infectious Disease

Investigators in the Pathogenesis of Infectious Disease

Grant Recipients

2007
2006
2005
2003
2002

 

2007

Benjamin K. Chen, M.D., Ph.D.
Mount Sinai School of Medicine
Dissemination of HIV through virological synapses

Andrew Darwin, Ph.D.
New York University School of Medicine
Mechanisms of Pseudomonas aeruginosa tolerance to secretin-induced stress during host infection

Michael R. Farzan, Ph.D.
Harvard Medical School
Parallel identification of obligate viral receptors

Britt Glaunsinger, Ph.D.
University of California-Berkeley
Global modulation of cellular gene expression by an oncogenic human herpesvirus

Karen J. Guillemin, Ph.D.
University of Oregon
Regulation of gut epithelial cell homeostasis by the microbiota

Lora V. Hooper, Ph.D.
University of Texas Southwestern Medical Center-Dallas
Innate immune responses to commensal bacteria at gut epithelial surfaces

Eckhard Jankowsky, Ph.D.
Case Western Reserve University
Molecular mechanisms of pathogen identification by the pattern recognition receptors RIG-I and MDA5

Barbara I. Kazmierczak, M.D., Ph.D.
Yale University
The role of injury in Pseudomonas aeruginosa pulmonary infection

Manuel Llinas, Ph.D.
Princeton University
Global analysis of the Plasmodium falciparum metabolome

Harmit S. Malik, Ph.D.
University of Washington
Evolution-based identification and functional study of intracellular host-virus interactions

Dorian B. McGavern, Ph.D.
The Scripps Research Institute
Chemical and molecular approaches to probe viral pathogenesis in real time

Yorgo Modis, Ph.D.
Yale University
Cell entry and innate immune recognition of flaviviruses

Neal Silverman, Ph.D.
University of Massachusetts Medical School
Intracellular bacterial recognition in the Drosophila innate immune response

Raphael H. Valdivia, Ph.D.
Duke University Medical Center
The role of secreted bacterial proteases in chlamydial pathogenesis

Andres Vazquez-Torres, D.V.M., Ph.D.
University of Colorado-Denver and Health Sciences Center-Fitzsimons Campus
Effects of nitrosative stress on bacterial two component regulatory systems in innate host defense

Ning Zheng, Ph.D.
University of Washington
Viral hijacking of host ubiquitin ligase machinery

2006

Choukri Ben Mamoun, Ph.D.
University of Connecticut Health Center
Function and regulation of host and parasite nutrient transporters during malaria infection

Helen E. Blackwell, Ph.D.
University of Wisconsin-Madison
Interception of bacterial quorum sensing with synthetic ligands

Blossom Damania, Ph.D.
University of North Carolina-Chapel Hill
Role of viral signaling proteins in the pathogenesis of Kaposi's sarcoma-associated herpes virus (KSHV)

Manoj T Duraisingh, Ph.D.
Harvard School of Public Health
Epigenetic control of virulence gene expression in Plasmodium falciparum

Peter J. Espenshade, Ph.D.
Johns Hopkins University School of Medicine
Oxygen-sensing and adaptation to host tissue hypoxia in the human fungal pathogen Cryptococcus neoformans

Robert F. Kalejta, Ph.D.
University of Wisconsin-Madison
Cellular and viral determinants of human cytomegalovirus lytic and latent replication cycles

Christian Munz, Ph.D.
Rockefeller University
Regulation of macroautophagy by viral infection

Kim Orth, Ph.D.
University of Texas Southwestern Medical Center-Dallas
VopL, a Vibrio effector that nucleates actin

Ana Rodriguez, Ph.D.
New York University School of Medicine
The role of hypoxanthine degradation in malaria-induced pathogenesis

Karla Fullner Satchell, Ph.D.
Northwestern University
A mouse model for the role of toxins in cholera pathogenesis

Luis M Schang, D.V.M., Ph.D.
University of Alberta
Silencing and antisilencing in the regulation of viral gene expression

Eric Skaar, Ph.D.
Vanderbilt University Medical Center
In vivo identification of Staphylococcus aureus proteins that defend against host neutrophils

Vanessa Sperandio, Ph.D.
University of Texas Southwestern Medical Center-Dallas
Interkingdom signaling in bacterial pathogenesis

Billy Tsai, Ph.D.
University of Michigan Medical School
How cholera toxin hijacks cellar machineries to transport across the ER membrane?

2005

Jody L. Baron, M.D., Ph.D.
University of California-San Francisco School of Medicine
Understanding immunopathogenesis of Hepatitis B virus

Matthew S. Bogyo, Ph.D.
Stanford University School of Medicine
Chemical mapping of proteolytic networks involved in Toxoplasma gondii pathogenesis

John H. Brumell, Ph.D.
University of Toronto
Recognition of bacteria in the cytosol of mammalian cells by protein conjugation systems

Tatjana Dragic, Ph.D.
Albert Einstein College of Medicine of Yeshiva University
Entry and intracellular trafficking of Hepatitis C virus

Michael S. Glickman, M.D.
Memorial Sloan-Kettering Cancer Center
Regulated intramembrane proteolysis in controlling Mycobacterium tuberculosis virulence and cell envelope composition

Akiko Iwasaki, Ph.D.
Yale University
Stromal cell contributions in innate and adaptive immune responses to mucosal viral infection

John S. Parker, B.V.M.S., Ph.D.
Cornell University College of Veterinary Medicine
Reovirus-induced apoptosis: the role of the viral outer-capsid protein mu1

Lalita Ramakrishnan, M.D., Ph.D.
University of Washington School of Medicine
Forward genetic screens in the zebrafish to identify host determinants of susceptibility to tuberculosis

Gregory A. Smith, Ph.D.
Northwestern University Feinberg School of Medicine
Coordination of herpes virus assembly and transport in axons of sensory neurons

Linda F. van Dyk, Ph.D.
University of Colorado Health Sciences Center
Analyzing tumor suppressors in the control of virus infection and inflammation

Sean P. Whelan, Ph.D.
Harvard Medical School
Exploration of the interaction of RNA viruses with their host cells

2003

David C. Bloom, Ph.D.
University of Florida College of Medicine
Identification of neuron-specific factors that regulate HSV-1 chromatin structure and transcription during latency

Dana A. Davis, Ph.D.
University of Minnesota-Twin Cities
Control of phenotypic switching and pathogenesis by the Mds3 protein

David A. Fidock, Ph.D.
Albert Einstein College of Medicine of Yeshiva University
Plasmodium falciparum transmembrane proteins and their role in parasite susceptibility to heme-binding antimalarials

Michael J. Gale, Jr. Ph.D.
University of Texas Southwestern Medical Center-Dallas
Control of hepatitis C virus replication

Andrew S. Neish, M.D.
Emory University School of Medicine
Transgenic analysis of prokaryotic effector proteins in the eukaryote, Drosophila melanogaster

Eric J. Rubin, M.D., Ph.D.
Harvard School of Public Health
Cell signaling by bacterial cytokines in Mycobacterium tuberculosis

Wenqing Xu, Ph.D.
University of Washington School of Medicine
Innate immunity: how do Toll-like receptors recognize microbial pathogens?

Thomas C. Zahrt, Ph.D.
Medical College of Wisconsin
Mycobacterium tuberculosis regulators modulating reactivation

2002

Barbara A. Burleigh, Ph.D.
Harvard School of Public Health
Functional characterization of the role of the host cell fibrogenic response in Trypanosoma cruzi infection

Zhijian J. Chen, Ph.D.
University of Texas Southwestern Medical Center-Dallas
Roles of TRAF5-regulated IKK activators in innate immunity

Maurizio Del Poeta, M.D.
Medical University of South Carolina-College of Medicine
Roles for inositol phosphoryl ceramide synthase 1 (IPC1) in fungal-host interaction

Heidi Goodrich-Blair, Ph.D.
University of Wisconsin-Madison
Pathogenesis of Xenorhabdus nematophilus in insects: a model for the innate immune response to bacterial pathogens

David B. Haslam, M.D.
Washington University-School of Medicine
Mechanisms of Shiga toxin translocation and intoxication within host cells

Margarethe (Meta) J. Kuehn, Ph.D.
Duke University Medical Center
Toxin trafficking via vesicles

C. Erec Stebbins, Ph.D.
Rockefeller University
Structural studies of bacterial virulence factors

Ren Sun, Ph.D.
University of California-Los Angeles-School of Medicine
Identification of cellular factors that determine the fate of herpes virus infection: latency versus lytic replication

Chloe L. Thio, M.D.
Johns Hopkins University School of Medicine
The identification of human genes associated with hepatitis B virus outcomes

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