Brian Druker, MD
Director, Knight Cancer Institute at Oregon Health & Science University
JELD-WEN Chair of Leukemia Research
Investigator, Howard Hughes Medical Institute
Brian Druker, MD, revolutionized the treatment of cancer through research that resulted in the first drug to target the molecular defect of cancer while leaving healthy cells unharmed. Marketed under the name Gleevec®, his discovery turned a once-fatal cancer, chronic myeloid leukemia, into a manageable condition.
Treatment with Gleevec received FDA approval in record time, was featured on the cover of Time magazine, and established Druker as a pioneer in the field of precision medicine. Most important, his discovery became a new proof of principal for targeted therapies, spurring the development of more than 50 similar precision therapies for other cancers.
Druker now is applying key principles of precision medicine to early detection. Earlier detection of lethal cancers represents the greatest opportunity to increase cancer survival rates. Thanks to $1 billion in philanthropic funding, Druker is developing a large-scale early detection program that builds upon the scientific strengths of OHSU’s Knight Cancer Institute.
Druker has been recognized with numerous awards, including the Warren Alpert Prize from Harvard Medical School, the Lasker-DeBakey Award for Clinical Medical Research, the Japan Prize in Healthcare and Medical Technology, and most recently, the 2018 Tang Prize in Biopharmaceutical Science. He has been elected to the National Academy of Medicine, the National Academy of Sciences and the American Academy of Arts and Sciences.