Investigators in the Pathogenesis of Infectious Disease

Grant Recipients 2002-2005

2005

Jody L. Baron, M.D., Ph.D.
University of California-San Francisco School of Medicine
Understanding immunopathogenesis of Hepatitis B virus

Matthew S. Bogyo, Ph.D.
Stanford University School of Medicine
Chemical mapping of proteolytic networks involved in Toxoplasma gondii pathogenesis

John H. Brumell, Ph.D.
University of Toronto
Recognition of bacteria in the cytosol of mammalian cells by protein conjugation systems

Tatjana Dragic, Ph.D.
Albert Einstein College of Medicine of Yeshiva University
Entry and intracellular trafficking of Hepatitis C virus

Michael S. Glickman, M.D.
Memorial Sloan-Kettering Cancer Center
Regulated intramembrane proteolysis in controlling Mycobacterium tuberculosis virulence and cell envelope composition

Akiko Iwasaki, Ph.D.
Yale University
Stromal cell contributions in innate and adaptive immune responses to mucosal viral infection

John S. Parker, B.V.M.S., Ph.D.
Cornell University College of Veterinary Medicine
Reovirus-induced apoptosis: the role of the viral outer-capsid protein mu1

Lalita Ramakrishnan, M.D., Ph.D.
University of Washington School of Medicine
Forward genetic screens in the zebrafish to identify host determinants of susceptibility to tuberculosis

Gregory A. Smith, Ph.D.
Northwestern University Feinberg School of Medicine
Coordination of herpes virus assembly and transport in axons of sensory neurons

Linda F. van Dyk, Ph.D.
University of Colorado Health Sciences Center
Analyzing tumor suppressors in the control of virus infection and inflammation

Sean P. Whelan, Ph.D.
Harvard Medical School
Exploration of the interaction of RNA viruses with their host cells

2003

David C. Bloom, Ph.D.
University of Florida College of Medicine
Identification of neuron-specific factors that regulate HSV-1 chromatin structure and transcription during latency

Dana A. Davis, Ph.D.
University of Minnesota-Twin Cities
Control of phenotypic switching and pathogenesis by the Mds3 protein

David A. Fidock, Ph.D.
Albert Einstein College of Medicine of Yeshiva University
Plasmodium falciparum transmembrane proteins and their role in parasite susceptibility to heme-binding antimalarials

Michael J. Gale, Jr. Ph.D.
University of Texas Southwestern Medical Center
Control of hepatitis C virus replication

Andrew S. Neish, M.D.
Emory University School of Medicine
Transgenic analysis of prokaryotic effector proteins in the eukaryote, Drosophila melanogaster

Eric J. Rubin, M.D., Ph.D.
Harvard School of Public Health
Cell signaling by bacterial cytokines in Mycobacterium tuberculosis

Wenqing Xu, Ph.D.
University of Washington School of Medicine
Innate immunity: how do Toll-like receptors recognize microbial pathogens?

Thomas C. Zahrt, Ph.D.
Medical College of Wisconsin
Mycobacterium tuberculosis regulators modulating reactivation

2002

Barbara A. Burleigh, Ph.D.
Harvard School of Public Health
Functional characterization of the role of the host cell fibrogenic response in Trypanosoma cruzi infection

Zhijian J. Chen, Ph.D.
University of Texas Southwestern Medical Center
Roles of TRAF5-regulated IKK activators in innate immunity

Maurizio Del Poeta, M.D.
Medical University of South Carolina-College of Medicine
Roles for inositol phosphoryl ceramide synthase 1 (IPC1) in fungal-host interaction

Heidi Goodrich-Blair, Ph.D.
University of Wisconsin-Madison
Pathogenesis of Xenorhabdus nematophilus in insects: a model for the innate immune response to bacterial pathogens

David B. Haslam, M.D.
Washington University-School of Medicine
Mechanisms of Shiga toxin translocation and intoxication within host cells

Margarethe (Meta) J. Kuehn, Ph.D.
Duke University Medical Center
Toxin trafficking via vesicles

C. Erec Stebbins, Ph.D.
Rockefeller University
Structural studies of bacterial virulence factors

Ren Sun, Ph.D.
University of California-Los Angeles-School of Medicine
Identification of cellular factors that determine the fate of herpes virus infection: latency versus lytic replication

Chloe L. Thio, M.D.
Johns Hopkins University School of Medicine
The identification of human genes associated with hepatitis B virus outcomes