Brenda Andrews, PhD
University Professor C.C., FRSC
Charles H. Best Chair of Medical Research
University of Toronto
Brenda Andrews is the Charles H. Best Chair of Medical Research, Director of the Donnelly Centre for Cellular and Biomolecular Research and Professor of Molecular Genetics at the University of Toronto.
Dr. Andrews completed her PhD in Medical Biophysics (with Paul Sadowski) at the University of Toronto, and postdoctoral training in genetics with the late Dr. Ira Herskowitz at the University of California San Francisco.
In 1991, Dr. Andrews was recruited to the Department of Medical Genetics (now Molecular Genetics) at the University of Toronto. She became Chair of the Department in 1999, a position she held for 5 years before assuming a position as Chair of the Banting & Best Department of Medical Research and as the inaugural Director of the Donnelly Centre. Dr. Andrews’ current research interests include analysis of genetic interaction networks in budding yeast and mammalian cells, using high through-put genetics platforms that include high content microscopy for systematic analysis of cell biological phenotypes. Dr. Andrews is a Companion of the Order of Canada, an elected Fellow of the Royal Society of Canada, the American Association for the Advancement of Science and the American Academy of Microbiology. She joined the BWF Board in October 2019.
Brian Druker, MD
Director, Knight Cancer Institute at Oregon Health & Science University
JELD-WEN Chair of Leukemia Research
Investigator, Howard Hughes Medical Institute
Brian Druker, MD, revolutionized the treatment of cancer through research that resulted in the first drug to target the molecular defect of cancer while leaving healthy cells unharmed. Marketed under the name Gleevec®, his discovery turned a once-fatal cancer, chronic myeloid leukemia, into a manageable condition.
Treatment with Gleevec received FDA approval in record time, was featured on the cover of Time magazine, and established Druker as a pioneer in the field of precision medicine. Most important, his discovery became a new proof of principal for targeted therapies, spurring the development of more than 50 similar precision therapies for other cancers.
Druker now is applying key principles of precision medicine to early detection. Earlier detection of lethal cancers represents the greatest opportunity to increase cancer survival rates. Thanks to $1 billion in philanthropic funding, Druker is developing a large-scale early detection program that builds upon the scientific strengths of OHSU’s Knight Cancer Institute.
Druker has been recognized with numerous awards, including the Warren Alpert Prize from Harvard Medical School, the Lasker-DeBakey Award for Clinical Medical Research, the Japan Prize in Healthcare and Medical Technology, and most recently, the 2018 Tang Prize in Biopharmaceutical Science. He has been elected to the National Academy of Medicine, the National Academy of Sciences and the American Academy of Arts and Sciences.
Terence S. Dermody, MD
Vira I. Heinz Professor and Chair of Pediatrics
Professor of Microbiology and Molecular Genetics
University of Pittsburgh School of Medicine
Physician-in-Chief and Scientific Director
Children’s Hospital of Pittsburgh of UPMC
Dr. Terence S. Dermody is the Vira I. Heinz Professor and Chair of Pediatrics at the University of Pittsburgh School of Medicine and Physician-in-Chief and Scientific Director at Children’s Hospital of Pittsburgh of UPMC. He also is Professor of Microbiology and Molecular Genetics at the University of Pittsburgh School of Medicine.
Dr. Dermody received his B.S. degree from Cornell University and his M.D. degree from Columbia University. He completed an internal medicine residency at Presbyterian Hospital in New York and fellowships in infectious diseases and molecular virology at Brigham and Women’s Hospital and Harvard Medical School. Prior to moving to Pittsburgh, Dr. Dermody was Dorothy Overall Wells Professor of Pediatrics and Director of the Medical Scientist Training Program and Division of Pediatric Infectious Diseases at Vanderbilt University School of Medicine.
Dr. Dermody is a virologist with interests in viral pathogenesis and vaccine development. Most of his research has focused on reovirus, an important experimental model for studies of viral encephalitis in the young, and chikungunya virus, an emerging mosquito-borne virus that causes epidemics of fever and arthritis. His research contributions have enhanced an understanding of how these viruses enter into host cells and cause organ-specific disease. He has published more than 220 articles, reviews, chapters, and editorials and has been recognized for his research accomplishments by the Vanderbilt Ernest W. Goodpasture Faculty Research Award, an NIH MERIT Award, and the American Society for Microbiology D. C. White Research and Mentoring Award.
Dr. Dermody is a member of the American Academy of Microbiology, American Pediatrics Society, American Society for Clinical Investigation, Association of American Physicians, and Society for Pediatric Research and a fellow of the American Association for the Advancement of Science. He is a past president of the American Society for Virology, past chair of the AAMC GREAT Group M.D.-Ph.D. Section Steering Committee, and current chair of the Virology Division of the International Union of Microbiological Societies. Dr. Dermody is an editor for the Journal of Virology and mBio and an associate editor for the Annual Review of Virology. He became a member of the Board of Directors of the Burroughs Wellcome Fund in 2015.
Professor Paula T. Hammond
Koch Professor of Engineering
Department Head of Chemical Engineering
Koch Institute of Integrative Cancer Research
Massachusetts Institute of Technology
Professor Paula T. Hammond is the David H. Koch Chair Professor of Engineering at the Massachusetts Institute of Technology, Head of the Department of Chemical Engineering and a member of MIT’s Koch Institute for Integrative Cancer Research. Her research in nanomedicine encompasses the development of new biomaterials to enable drug delivery from surfaces with spatio-temporal control. She also investigates novel responsive polymer architectures for targeted nanoparticle drug and gene delivery.
Professor Paula Hammond was elected into, the National Academy of Science in 2018, the National Academy of Engineering in 2017, the National Academy of Medicine in 2016, and the 2013 Class of the American Academy of Arts and Sciences. Professor Hammond has published over 330 papers, and over 20 patent applications. She is the co-founder and member of the Scientific Advisory Board of LayerBio, Inc. and a member of the Scientific Advisory Board of Moderna Therapeutics.
Dr. Robert Lefkowitz
Professor of Medicine
James B. Duke Distinguished Professor of Medicine
Professor of Biochemistry
Professor of Pathology
Professor of Chemistry
Member of the Duke Cancer Institute
Robert Lefkowitz was born on April 15, 1943, in The Bronx, New York.
After graduating from the Bronx High School of Science in 1959, he attended Columbia College from which he received a bachelor of arts in chemistry 1962.
He graduated from Columbia University College of Physicians and Surgeons in 1966 with an M.D. Degree. After serving an internship and one year of general medical residency at Columbia Presbyterian Medical Center, he served as Clinical and Research Associate at the National Institutes of Health from 1968 to 1970.
Upon completing his medical residency and research and clinical training in 1973, he was appointed Associate Professor of Medicine and Assistant Professor of Biochemistry at the Duke University Medical Center. In 1977 he was promoted to Professor of Medicine and in 1982 to James B. Duke Professor of Medicine at Duke University. He is also Professor of Biochemistry and Chemistry. He has been an Investigator of the Howard Hughes Medical Institute since 1976 and was an Established Investigator of the American Heart Association from 1973-1976.
He has served as President of the American Society for Clinical Investigation and of the Association of America Physicians, and on the Council of the USA National Academy of Sciences.
In 1988, he was inducted into both the National Academy of Sciences and the American Academy of Arts and Sciences, and in 1994, he was elected to the Institute of Medicine of the National Academy of Sciences.
Lefkowitz has received many awards for his work on cellular receptors, including the Gairdner Foundation International Award (1988), the Association of America Medical Colleges’ Biomedical Research Award (1990), the American Heart Association’s Basic Research Prize (1990) and its Research Achievement Award (2009), the Bristol-Myers Squibb Award for Distinguished Achievement in Cardiovascular Research (1992), the National Academy of Sciences’ Jessie Stevenson Kovalenko Medal (2001), Fred Conrad Koch Award of The Endocrine Society (2001), and five honorary doctorates. In 2007 he received the Albany Medical Center Prize in Medicine and Biomedical Research and The Shaw Prize in Life Science and Medicine. He received the 2007 National Medal of Science, presented by President George W. Bush on Sept. 29, 2008, in a White House ceremony and the Nobel Prize in Chemistry in 2012.
He joined the Burrough Wellcome Fund Board of Directors in October 2019.
Wendell Lim, PhD
Professor and chair, Department of Cellular and Molecular Pharmacology
University of California – San Francisco
Howard Hughes Medical Institute Investigator
director, UCSF Center for Systems & Synthetic Biology
Wendell Lim, PhD, is interested in understanding how genetically encoded molecular programs can yield the remarkable behaviors observed in biological organisms, at multiple scales. He received his undergraduate degree at Harvard University and a doctoral degree at MIT, as well as completing a postdoctoral fellowship at Yale University. Now chair and professor of cellular and molecular pharmacology at UC San Francisco, Lim began his research career as a biophysical chemist and structural biologist studying problems such as the evolutionary optimization of enzymes, how protein structure is encoded in sequence, and the determinants of protein-protein interaction specificity. His research has gradually shifted towards utilizing this mechanistic understanding of molecules as a foundation to study how systems of interacting molecules assemble to yield cellular or organismal signaling behaviors – complex behaviors in both space and time. His lab is interested in both the fundamental principles governing these molecular programs, as well as the way such programs have evolved. How to identify the most relevant functional modules at various scales of biology is an ongoing but fascinating challenge. We have also become interested in using synthetic biology and our growing understanding of molecular networks to engineer cells with novel behaviors, such as therapeutic immune cells programmed to recognize and treat cancer or other diseases. A Howard Hughes Medical Institute Investigator, Lim is director of the UCSF Center for Systems and Synthetic Biology and is the scientific founder of Cell Design Labs, a company pioneering advanced cell therapies. Dr. Lim joined the Burroughs Wellcome Fund Board of Directors in October 2018.
Kelsey Martin, MD, PhD (Chair)
Dean for the David Geffen School of Medicine
Professor of Biological Chemistry and Psychiatry and Biobehavioral Sciences
University of California-Los Angeles
Dr. Kelsey Martin is the Dean for the David Geffen School of Medicine at UCLA and a Professor in the Departments of Biological Chemistry and Psychiatry and Biobehavioral Sciences. Outside UCLA, In addition to being a Senior Fellow at the Howard Hughes Medical Institute Janelia Research Campus, Dr. Martin serves on the editorial board of Cell, the board of directors for the Burroughs Wellcome Fund, the selection committee of the McKnight Scholar Awards and the board of directors of the McKnight Endowment Fund for Neuroscience. Dr. Martin served as co-director of the UCLA-Caltech Medical Scientist Training Program from 2005-2013, Chair of the Department of Biological Chemistry from 2010-2015, Chair of the Neuroscience Research Theme Committee from 2013-2015 and Chair of the David Geffen School of Medicine Basic Science Chairs from 2012-2015. She was named Executive Vice Dean and Associate Vice Chancellor at the Geffen School of Medicine.
Dr. Martin received her B.A. in English and American Language and Literature at Harvard University. After serving as a Peace Corps volunteer in the Democratic Republic of Congo, she entered the MD-PhD program at Yale University where she studied influenza virus-host cell interactions in the laboratory of Dr. Ari Helenius, receiving her PhD degree in Molecular Biophysics and Biochemistry and her MD degree in 1992. She went on to complete her postdoctoral training in neurobiology with Dr. Eric Kandel at Columbia University and joined the UCLA faculty in 1999.
Dr. Martin directs a productive research laboratory focused on understanding how experience changes connectivity in the brain to store long-term memories. While many aspects of brain circuitry are hard-wired, it is also dynamic: the connections between neurons in the brain change with experience to store information, and in this way, nature and nurture combine to define our identities. Conversely, experiences that produce maladaptive changes in brain circuitry underlie many neuropsychiatric disorders, and age-related decreases in brain plasticity contribute to age-related memory disorders such as Alzheimer’s disease. Long-lasting changes in brain connectivity require new gene expression, and Dr. Martin has discovered a role for specific signaling molecules that travel from stimulated synapses to the nucleus to change the transcription of DNA to RNA. Her research also has highlighted a central role for the localization of RNAs to synapses, where their synthesis into protein is regulated by neuronal activity, and that the process of local protein synthesis is likely to play a particularly important role in autism spectrum disorders.
She joined the BWF Board of Directors in October 2015.
Louis J. Muglia, MD, Phd
President and CEO
Burroughs Wellcome Fund
Louis J. Muglia, MD, PhD, is the President and CEO of the Burroughs Wellcome Fund. a private foundation located in Research Triangle Park, NC.
Prior to joining the Fund, Dr Muglia was the Vice Chair for Research, A. Graeme Mitchell Chair of the Division of Human Genetics, Co-Director of the Perinatal Institute and Director of the Center for Prevention of Preterm Birth at Cincinnati Children’s Hospital Medical Center, and Professor of Pediatrics at the University of Cincinnati College of Medicine.
Dr. Muglia has been involved with the Burroughs Wellcome Fund for more than 20 years. First, as a recipient of a Career Award in the Biomedical Sciences in 1995 from the Fund and then as a member of the Advisory Committee for the Career Awards in the Medical Sciences program. He has also been actively involved in the Reproductive Science funding area, serving on and chairing the advisory committee for the Preterm Birth Initiative.
Dr. Muglia has pioneered advances in analyzing hormones as they relate to the birth process and the maternal genetic response. By analyzing this response, it may help determine whether or not a mother is at risk to deliver a preterm birth or babies born before 37 weeks. Preterm birth is a major health and social challenge since preterm birth may lead to long-term health problems and development difficulties. His group has identified genetic regions in the mother’s genome that affect risk for preterm birth and provide new targets for prevention.
Among Dr. Muglia’s achievements are more than 260 publications and many awards, including a Burroughs Wellcome Fund Career Development Award in the Biomedical Sciences, the Society of Pediatric Research Young Investigator Award, and election to the American Society for Clinical Investigation and Association of American Physicians. Dr. Muglia was also elected as a Fellow in the American Association for the Advancement of Science and to membership in the National Academy of Medicine. He is an active member of the Society for Pediatric Research, Society for Neuroscience, and the Pediatric Endocrine Society. Dr. Muglia served as chair of the Board of Scientific Counselors for the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health.
Prior to joining Cincinnati Children’s, Dr. Muglia was Edward Claiborne Stahlman Professor and Vice Chair for Research Affairs in Pediatrics at Vanderbilt University Medical Center, and Alumni Endowed Professor of Pediatrics at Washington University in St. Louis.
Dr. Muglia earned his Doctor of Medicine and Doctor of Philosophy degrees from the University of Chicago. He received a Bachelor of Science degree in biophysics from the University of Michigan.
Lauretta (Retz) Reeves, CFA, AWMA
International Portfolio Manager
Islamorada Investment Management
Retz Reeves is the international equities portfolio manager at Islamorada Investment Management (IIM) and utilizes a value-based approach. Ms. Reeves joined IIM in 2013. She has served as a portfolio manager and Co-Chief Investment Officer of the Value Strategy at Hansberger Global Investors (HGI). Before HGI, Ms. Reeves was a portfolio manager and Senior Vice President with Franklin Templeton Investments. She is a CFA® Charter Holder and a member of the CFA Institute and The CFA Society of South Florida. Also, she holds the designation of Accredited Wealth Management Advisor (SM) (“AWMA”) from the College of Financial Planning. She received a BBA from Florida International University with High Honors and an MBA from Nova Southeastern University. She is a member of the Baptist Hospital Foundation Founders’ society and the Upper Keys Century Business and Professional Women. Ms. Reeves also serves as a mentor for Take Stock in Children.
Christine Seidman, MD
T.W. Smith Professor of Medicine & Genetics
Investigator of Howard Hughes Medical Institute
Director, Brigham & Women’s Cardiovascular Genetics Center
Christine Seidman, MD is the Thomas W. Smith Professor of Medicine and Genetics at Harvard Medical School and Brigham and Women’s Hospital. She is an Investigator of the Howard Hughes Medical Institute. She was an undergraduate at Harvard College and received a M.D. from George Washington University School of Medicine. After clinical training in Internal Medicine at John Hopkins Hospital Seidman received subspecialty training in cardiology at the Massachusetts General Hospital.
Seidman practices at the Brigham and Women’s Hospital, where she is the founding Director of the BWH Cardiovascular Genetics Center. Composed of a multidisciplinary team of physicians and scientists, the BWH Cardiovascular Genetics Center provides unparalleled care to patients with cardiomyopathies and their families. Through her translation of basic science discoveries, the BWH Cardiovascular Genetics Center has transformed the clinical diagnosis and management of cardiomyopathies and is defining innovative treatment strategies.
Seidman directs a basic research program that focuses on the discovery of genes, mutations, and mechanisms for human heart muscle disorders, particularly cardiomyopathies and congenital heart defects. Translation of these fundamental discoveries has enabled gene-based diagnosis and novel therapeutic targets. Her accomplishments have garnered many honors, including the Fondation Lefoulon-Delande Le Grande Prix for Cardiovascular Research awarded by the Academie de Science, – Institut de France, Distinguished Scientist Award of the American Heart Association, Fellow of the American Academy of Arts and Sciences, and membership in the National Academy of Medicine and the National Academy of Sciences. Dr. Seidman is also a former president of the Association of American Physicians.
Jenny Ting, PhD
William Rand Kenan Professor of Genetics
Immunology Program Leader, Lineberger Comprehensive Cancer Center
Director, UNC Center for Translational Immunology
Co-Director, Institute of Inflammatory Disease
University of North Carolina-Chapel Hill
Dr. Jenny Ting received her Ph.D. in Microbiology and Immunology from Northwestern University in Chicago, IL and postdoctoral training at the University of Southern California and Duke University. She joined the faculty at the University of North Carolina, Chapel Hill as an Assistant Professor and has been there since that time. Currently, she is a William Rand Kenan Professor of Genetics and the UNC Lineberger Comprehensive Cancer Center’s Immunology Program Leader. She is also the Director of the UNC Center for Translational Immunology and the co-Director of the Institute of Inflammatory Diseases.
From 2008 to 2014, she served as the co-Director of the Southeast Regional Center for Excellence in Emerging Infections and Biodefense (SERCEB). She is currently the Program Director of an NIAID-funded Center for Translational Research, NIAID-funded Center for Immune-mediated Viral Control, a National Multiple Sclerosis Society (NMSS) funded Collaborative Multiple Sclerosis Center and an NIH training grant. She has trained more than 90 postdoctoral fellows and students who have gone on to successful scientific careers ranging from deanship, chairmanship, professors and industrial leaders.
Nationally, Dr. Ting has served on multiple NIH advisory boards, as well as committees for the NMSS, Burroughs Wellcome Fund, and American Asthma Foundation. She has been awarded the American Society of Microbiology Award for Outstanding Contributions to the Field of Immunology and Immunity and selected as the 2013 American Association of Immunology prestigious Life Technologies Awardee. She is an elected member of the Academia Sinica in Taiwan and the American Association of Immunologists council.
She has pioneered new areas of innate immunity, most notably reporting the first study describing the entire human NOD-like receptor family and continued to be a leader in this field. Her work combines fundamental innate immunology with molecular biology and she has reported extensively on the impact of innate immunity in infection, autoimmunity, cancer, microbiome composition and metabolic disorders. She has published over 280 articles, many in top journals. She joined the Fund’s Board of Directors in February 2017.
Honorary Board Member
Philip R. Tracy
Smith, Anderson, Blount, Dorsett, Mitchell & Jernigan, L.L.P.
Mr. Tracy received his undergraduate degree from the University of Nebraska and law degree from George Washington University. He joined Burroughs Wellcome Co. in 1974 as assistant general counsel, and he served as the company’s president and the chief executive officer from 1989 until its sale to Glaxo in 1995. Mr. Tracy currently is associated with the North Carolina-based law firm of Smith, Anderson, Blount, Dorsett, Mitchell & Jernigan, L.L.P. and is a Venture Partner with InterSouth Partners, an early stage Venture Fund located in Durham, North Carolina. He serves on the board of directors of several companies and non-profit organizations. Mr. Tracy served on the BWF board from 1989-1996 and again from 2001-2008.