Career Awards at the Scientific Interface

Application Deadline:

Jan 08, 2021

by

4:00pm

ET

Status:

Invited Applicants Only

Eligibility & Application Process:

For a full explanation of the eligibility requirements, view the Request for Proposals.

Request for Proposals

Grant Recipients

2020

Ahmed S. Abdelfattah, PhD Brown University Probing and manipulating the neural circuitry of opiate addiction using novel optogenetic tools

Zibo Chen, PhD California Institute of Technology Molecular programming using de novo designed proteins

Yogesh Goyal, PhD  University of Pennsylvania Biochemical trajectories guiding rare cell plasticity and therapy resistance in single cancer cells

Elizabeth R. Jerison, PhD  Stanford University Migration and population dynamics in the zebrafish adaptive immune system

Stephanie E. Lindsey, PhD Stanford University Quantitation of early great vessel growth and remodeling

Brittany S. Morgan, PhD TBD* Cracking the molecular recognition code: capturing dynamic substructures with small molecules

Cristina Rodriguez, PhD  University of California - Berkeley Decoding spinal cord neural circuits through advanced optical imaging methods

Julea Vlassakis, PhD University of California-Berkeley Precision oncology via single-cell proteomics

*award will be granted to faculty institution of award recipient

2019

Steven Mark Banik, PhD  Stanford University Reprogramming proteins for targeted degradation and intracellular trafficking

Jennifer Ann Noelani Brophy, PhD Stanford University Engineering organ development using synthetic genetic regulation

Fei Chen, PhD  Massachusetts Institute of Technology Genomic tools for understanding spatial and dynamic organization of biological tissues

Víctor García-López, PhD Rice University Molecular machines target, disrupt cell membranes, and kill cancer cells and resistant bacteria

Livnat Jerby, PhD  Massachusetts Institute of Technology Deciphering immune evasion mechanisms in cancer with single-cell technologies

Christina K. Kim, PhD  Stanford University Simultaneous molecular activity recording and transcriptomics of brainwide neural ensembles

Joseph William Larkin, PhD University of California-San Diego Patterning microbial populations through collective dynamics

Jeffrey E. Markowitz, PhD Harvard Medical School Resolving the neural mechanisms of reinforcement learning through new behavioral and optical technologies

Sergey D. Stavisky, PhD  Stanford University Brain-computer interfaces to actualize the movements and speech of people with paralysis

Jeffrey Robert Tithof, PhD University of Rochester Experimentally-validated simulations of cerebrospinal fluid flow through the brain’s perivascular network

Mark Wagner, PhD Stanford University Computations, recurrent dynamics, and learning in the cortex-cerebellum circuit underlying skilled behavior

2018

Gozde Durmus, DPhil, PhD Stanford University Levitating rare biological materials to decode the fundamentals

Kirsten L. Frieda, PhD California Institute of Technology Recording cell histories in situ using MEMOIR

Walter Gabriel Gonzalez, PhD California Institute of Technology Dynamic control of brain activity and behavioral robustness

Brandon Helfield, PhD University of Toronto Biophysics and cell biology of ultrasound-assisted membrane permeabilization for targeted gene delivery

Daniel R. Hochbaum, PhD Harvard Medical School Parsing learning-dependent circuit remodeling from spatiotemporally resolved cell states

Chiamaka Denise Okafor, PhD Emory University Targeting steroid receptors by uncovering evolutionary mechanisms of activation

Nicolas Christian Pegard, PhD University of California-Berkeley Computational optical interfaces for neurosciences and systems biology

Calin Plesa, PhD University of California-Los Angeles Ubiquitous biosensing through engineered histidine kinases

Silvia Rouskin, PhD Massachusetts Institute of Technology Understanding RNA structure heterogeneity and its role in gene expression and disease

Geoffrey Schiebinger, PhD Massachusetts Institute of Technology Analyzing developmental processes with optimal transport

Shahrzad Yazdi, PhD Massachusetts Institute of Technology Bridging the origin and function of flows in developmental biology

2017

Scott E. Boyken, PhD University of Washington Programmable protein interaction specificity to engineer and interrogate cellular signaling

Gregg A. Duncan, PhD Johns Hopkins University Microscale airway surface liquid interactions and their role in obstructive lung diseases

Felipe Garcia Quiroz, PhD Rockefeller University Repetitive elements of life: from genomes to proteins and material systems

Kelley Harris, PhD Stanford University Decoding the evolutionary history of DNA replication fidelity from whole genome sequences

Felix JH Hol, PhD Stanford University Eco-evolutionary dynamics of mosquito-borne viruses

Ashok Litwin-Kumar, PhD Columbia University Modeling distributed olfactory learning in rodents and insects

Po-Ru Loh, PhD Harvard School of Public Health Toward an early-warning system for leukemia: Characterizing mosaic copy number abnormalities

Tatiana V. Mishanina, PhD University of Wisconsin-Madison Visual-kinetic studies of pausing by bacterial RNA polymerase using time-resolved cryo-EM

Octavio Mondragon-Palomino, PhD California Institute of Technology In situ dissection of bacteria-bacteria interactions on the mucosa of the mammalian gut

Priya Moorjani, PhD Columbia University Learning about the rate and chronology of human evolution

Amy Elizabeth Shyer, PhD University of California-Berkeley Investigating mechano-chemical mechanisms of mesenchymal morphogenesis in skin and bone

Amy M. Weeks, PhD University of California-San Francisco Untangling the protease web: Chemical and enzymatic probes for dissection of proteolytic signaling in immune cells

2016

Ahmet F. Coskun, Ph.D. California Institute of Technology Computational single molecule imaging and barcoding: Exploring cellular identity at the single cell transcript level

Alexander G. Huth, Ph.D. University of California-Berkeley Comprehensive functional mapping of human cortex using generative models

Ashley Laughney Bakhoum, Ph.D. Sloan-Kettering Institute Uncovering transcriptional vulnerabilities in latent metastasis

Michael J. Mitchell, Ph.D. Massachusetts Institute of Technology High-throughput in vivo nucleic acid delivery screening via molecular barcoding of nanoparticles for bone marrow-related diseases

Arthur Prindle, Ph.D. University of California-San Diego Electrical signaling and multicellular organization

Adrianne Marie Rosales, Ph.D. University of Colorado-Boulder Dynamic viscoelastic hydrogels to study mechanisms of fibrosis

David M. Schneider, Ph.D. Duke University Neural circuits for making predictions and learning from mistakes

Amy Wesolowski, Ph.D. Princeton University Impact of human travel on infectious disease dynamics

Jing Yan, Ph.D. Princeton University Resolving and analyzing living bacterial biofilms at the single cell level

Weijian Yang, Ph.D. Columbia University Holographic mapping and manipulation of neuronal microcircuits

2014

Ariana E Anderson, Ph.D. University of California-Los Angeles It's all in your head: isolating the placebo effect in the brain to reduce drug development costs

Amit Choudhary, Ph.D. Harvard University / Broad Institute Snakes, antioxidants, and diabetes

Matthew C Good, Ph.D. University of California-Berkeley Cell size and shape dependence of intracellular assembly and signaling

Prashant Mali, Ph.D. Harvard Medical School Engineering normal and diseased liver organogenesis

Nikhil S Malvankar, Ph.D. University of Massachusetts-Amherst Direct visualization of charge flow in individual native biomolecules

Elizabeth A Nance, Ph.D. Johns Hopkins University Nanoparticle-mediated targeted therapies for pediatric brain disorders

Elizabeth Hesper Rego, Ph.D. Harvard School of Public Health Drug use on the single cell level: differential antibiotic susceptibility of mycobacterial cells using fluorescent reporters.

Ramkumar Sabesan, Ph.D. University of California-Berkeley School of Optometry Studying visual function on a cellular scale

Kimberly Murley Stroka, Ph.D. Johns Hopkins University School of Medicine Engineering blood-brain barrier mechanobiology in tumor metastasis

Michael D. Vahey, Ph.D. University of California-Berkeley School of Public Health Uncovering the dynamics of enveloped virus assembly

Heng Xu, Ph.D. Baylor College of Medicine Deciphering stochastic transcriptional regulation at the single-event level

Xin Zhang, Ph.D. Scripps Research Institute Scrutinizing the cellular and molecular mechanisms that create and maintain the functional proteome using chemical probes

2013

Gregory R. Bowman, Ph.D. University of California - Berkeley Decrypting cryptic allosteric sites resulting from protein flexibility

Yaniv Erlich, Ph.D. Whitehead Institute for Biomedical Research Dissecting complex phenotypes using web 2.0 social networks

Stephanie I. Fraley, Ph.D. Johns Hopkins University School of Medicine Digitizing microRNA: integrated profiling and discovery for rapid, quantitative, and broad-scale detection in infectious disease

Hernan G. Garcia, Ph.D. Princeton University Wiring up the synthetic fly

Karen E. Kasza, Ph.D. Memorial Sloan-Kettering Cancer Center Mechanical cues coordinating cell behaviors during morphogenesis

Gabriel Kwong, Ph.D. Massachusetts Institute of Technology Nanoparticles that amplify biomarkers in vivo for ultrasensitive metastasis monitoring

Megan N. McClean, Ph.D. Princeton University Optogenetic and microfluidic tools for generating dynamic inputs to interrogate and control biological networks

Mikhail G. Shapiro, Ph.D. University of California - Berkeley Genetically encoded reporters for sensitive non-invasive imaging of biological function

Paul A. Sigala, Ph.D. Washington University Mechanistic probes of heme metabolism in malaria parasites

Bo Wang, Ph.D. University of Illinois-Urbana-Champaign In vivo imaging and functional genomic analysis of stem cells in human parasitic worm schistosoma

2012

Buz M. Barstow, Ph.D. Harvard Medical School Evolving the limits of metabolism and in vivo catalysis

ShiNung Ching, Ph.D. Harvard Medical School Towards treatments in disorders of consciousness and new models of general anesthesia

Kwanghun Chung, Ph.D. Stanford University Clear, Lipid-exchanged, Anatomically Rigid, Imaging/immunostaining-compatible, Tissue hYdrogel (CLARITY) technology for high-throughput and high-content whole tissue analysis

Robert Gregg, Ph.D. Northwestern University From machine to biomimetic control in robot-assisted walking

Maureen E. Hillenmeyer, Ph.D. Stanford University In vivo synthetic evolution of bioactive natural products

Allon Moshe Klein, Ph.D. Harvard Medical School Defining patterns and mechanisms of stem cell fate choice

Sergey A. Kryazhimskiy, Ph.D. Harvard University Predicting evolution in microbial populations

Heather J. Kulik, Ph.D. Stanford University Deciphering the role of the protein scaffold in enzyme catalysis with fast and accurate computation

Lulu Qian, Ph.D. California Institute of Technology Exploring and re-realizing the principles of information processing in biology using artificial nucleic-acid systems

Jesse G. Zalatan, Ph.D. University of California - San Francisco Entropic contributions to efficiency in biochemical networks

Award Timeline

Jan 08, 2020

Invites for full proposal

Sep 01, 2020

Pre-proposal Deadline

Nov 20, 2020

Invites for full proposal

Jan 08, 2021

Application Deadline

Jun 01, 2021

Notice of Award

Sep 01, 2021

Award Start Date

Jun 30, 2026

Award End Date

Program Contacts

Kelly Rose, PhD

Program Officer

919-991-5120

Melanie Scott

Senior Program Associate

919-991-5107