Preterm Birth Initiative

Grant Recipients

2017

John Anthony Capra Ph.D.
Vanderbilt University
Integrating 'omics and electronic health records to elucidate the genetic architecture of preterm birth

Jonghwan Kim Ph.D.
University of Texas-Austin
Identifying genetic factors controlling normal and abnormal placental development

Tippi C. MacKenzie M.D.
University of California-San Francisco
A precision medicine approach to detect dysbiosis and immune activation in preterm birth

Kimani C. Toussaint Ph.D.
University of Illinois-Urbana-Champaign
Investigating the mechanobiology of cervical remodeling using a novel combination of optical microscopy and nanoindentation

Ge Zhang M.D., Ph.D.
University of Cincinnati
Genomic study of gestational length and preterm birth

2015

Senad Divanovic, Ph.D.
University of Cincinnati
Role of type I IFNs/IFNAR axis in inflammation-induced preterm birth

Laura Marie Ensign, Ph.D.
Johns Hopkins University
The role of vaginal progesterone delivery in cervical remodeling and preterm birth

John James Moore, M.D.
Case Western Reserve University
Determination of the Mechanisms of Preterm Premature Fetal Membrane Rupture Using a Novel in-vitro Model System

Mark Phillippe, M.D.
Harvard Medical School
Cell-free Fetal DNA - the Trigger for Spontaneous Parturition

Timothy York, Ph.D.
Virginia Commonwealth University
Epigenetic mechanisms of preterm birth in a racially mixed sample of pregnant women

2014

Trevor D. Burt, M.D.
University of California-San Francisco
Fetal immune activation and lineage switching in preterm labor

Kang Chen, Ph.D.
Wayne State University
The functions of B cells in pregnancy and the pathogenesis of preterm birth

David N. Cornfield, M.D.
Stanford University School of Medicine
Myometrial smooth muscle cell TRPV channel activity modulates contractility

Stephen Lye, Ph.D.
University of Toronto
Targeting leukocyte activation to prevent preterm labor

Vincent Joseph Lynch, Ph.D.
University of Chicago
Evolutionary forward genomic insights into the casual mechanisms of preterm birth

2013

George Scott Worthen, M.D.
University of Pennsylvania
Genetics of preterm birth

Francesco J. DeMayo, Ph.D.
Baylor College of Medicine
Progesterone receptor regulation of gravid myometrium

Amanda L. Lewis, Ph.D.
Washington University
Mucus barrier degradation in bacterial vaginosis-associated preterm birth

Claire Chougnet, Ph.D.
University of Cincinnati
Host-microbe cross-talk and pregnancy outcomes

Katharina Ribbeck, D.Phil., Ph.D.
Massachusetts Institute of Technology
Properties and functions of cervical mucus associated withpreterm birth

2011

Kjersti M. Aagaard-Tillery, M.D., Ph.D.
Baylor College of Medicine
Contributions of maternal-fetal-mitochondrial genome and microbiome interactions to preterm birth

Julie Baker, Ph.D.
Stanford University
Genomic networks that guide trophoblast invasion and disease

Mala S. Mahendroo, Ph.D.
University of Texas Southwestern Medical Center-Dallas
Assessment of cervical ripening by sodium magnetic resonance imaging

Jeffrey C. Murray, M.D.
University of Iowa
Genomic signatures of gene expression and alternative splicing in preterm birth

Indira Mysorekar, Ph.D.
Washington University
Occult infections in the etiology of preterm birth

2009 (Planning Grants)

Kjersti M. Aagaard-Tillery, M.D., Ph.D.
Baylor College of Medicine
Contributions of maternal-fetal-mitochondrial genome and microbiome interactions to preterm birth

Vikki M. Abrahams, Ph.D.
Yale University
The role of placental Nod-like receptors in infection-associated preterm labor

Julie Baker, Ph.D.
Stanford University
Genomic networks that guide trophoblast invasion and disease

Ronald W. Davis, Ph.D.
Stanford University
Unexplained Preterm birth

Michal Elovitz, M.D.
University of Pennsylvania
Targeting novel pathways in cervical remodeling for predicting prematurity: a combined biomarker and genomics approach

Michael Douglas House, M.D.
Tufts Medical Center
Beyond cervical length: development of a patient-specific model of cervical mechanical function in pregnancy pregnancy

Mala S. Mahendroo, Ph.D.
University of Texas Southwestern Medical Center-Dallas
Assessment of cervical ripening by sodium magnetic resonance imaging

Jeffrey C. Murray, M.D.
University of Iowa
Genomic signatures of gene expression and alternative splicing in preterm birth

Indira Mysorekar, Ph.D.
Washington University
Occult infections in the etiology of preterm birth

Carl P. Weiner, M.D., M.B.A.
University of Kansas
Initiator-effector gene sets regulating myometrial contractility during term and preterm labor